微生物を利用した光学活性なC3合成ユニットの開発とその応用

抄録

We developed to produce optically pure glycerol derivatives, such as (R) and (S)-2, 3- dichloro-1-prop-anols, and (R) and (S)-3-chloro-1, 2-propanediols, based on microbial resolution. These compounds are precursors of optically active epichlorohydrins and glycidols which are used for wide variety of organic syntheses. We describe here the new methods to obtain these chiral C3 units and their several synthetic applications.