生体高分子のX線解析

最近の進歩

抄録

During the last decade, we have witnessed significant advances in various technological aspects of a discipline called “protein crystallography” which is a branch of the technique of X-ray crystal structure analyses specifically aimed at solving the crystal structures (and thus the molecular structures) of biological macromolecules. After the introductory sections dealing with 1) the relationship of the present field with organic chemistry and 2) the rationale for further promotion of the technique of protein crystallography, the advances in various technological aspects are summarized in the form of Table 1. Finally more detaild accounts are given for 1) the method and prospect of time-resolved X-ray crystal structure analysis using the Laue method and 2) the present situation of the Brookhaven Protein Data Bank.