Asymmetric Heck Reaction : Catalytic Asymmetric Syntheses of Bioactive Molecules

Abstract

The asymmetric Heck reaction, which we achieved for the first time several years ago, has been successfully applied to catalytic asymmetric syntheses of many bioactive molecules such as vernolepin, γ-butyrolactone derivatives, eptazocine, a halenaquinol skeleton and lentiginosine.