有機テルル化合物を用いた新しいラジカルカップリング反応

抄録

Organotellurium compounds reversibly generate carbon-centered radicals upon photolysis and thermolysis, and the radicals thus generated can be used for carbon-carbon bond formation with a variety of radical acceptors. For example, a variety of organotellurium compounds react with quinones to give the corresponding adducts, including polyprenyl qnuinonoids. The reaction of telluroglycosides and alkynes also gives the corresponding C-glycosides bearing vinyl telluride moiety. Isonitriles are also good acceptors and gives group-transfer products. Because the coupling reaction proceeds in a group-transfer manner, the carbon-tellurium bond in the products can be used for further synthetic transformation. Thus, the radical-mediated coupling followed by an adequate transformation provides a new versatile method in organic synthesis.