2002 年 60 巻 8 号 p. 740-751
In recent years there has been a broadly expanding interest in the synthesis of α-fluorophos-phonates. This interest has resulted from their potential utilities as mimics for biological phos-phates in the biological processes. This review is focussed on the recent development for the effi-cient synthesis of α-fluorophosphonates. The examples cited in this review are divided in four dis-tinct types of methods : (a) fluorination of phosphonates, (b) C-C bond formation of activated fluo-romethylphosphonate, (c) phosphonylation of fluoroolefins, (d) transformations of α-fluorophos-phonates.