Due to its clean combustion and high heating value, hydrogen fuel has attracted much interest from 1990s. It is crucial to develop safe and efficient hydrogen storage material for practical applications. In recent years, porousmetal-organic frameworks (MOFs) have been identified as promising adsorbents for H2 storage. They provide unique systems with large surface areas and precise molecular structures. This review will focus on the development of highly efficient MOFs for H2 storage.