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Volume 26 (1973)
- Issue 6 Pages 501-
- Issue 5 Pages 427-
- Issue 4 Pages 321-
- Issue 3 Pages 197-
- Issue 2 Pages 89-
- Issue 1 Pages 1-
Predecessor
Volume 26, Issue 5
Displaying 1-8 of 8 articles from this issue
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HIROO TAKAYAMA1973 Volume 26 Issue 5 Pages 427-438
Published: October 25, 1973
Released on J-STAGE: May 17, 2013
JOURNAL FREE ACCESS -
OSAMU KOBAYASHI, YOSHIO TSUMURA1973 Volume 26 Issue 5 Pages 439-442
Published: October 25, 1973
Released on J-STAGE: May 17, 2013
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AKIO KOBAYASI, HIROSHI AMEMIYA, TOMONOBU TAJIMA, YOJI MOTOIKE1973 Volume 26 Issue 5 Pages 443-448
Published: October 25, 1973
Released on J-STAGE: May 17, 2013
JOURNAL FREE ACCESSAlmost all Bacteroides strains isolated from the clinical specimens were susceptible to chloramphenicol, clindamycin and lincomycin in vitro.
Clinical response to lincomycin treatment was investigated in 4 cases of Bacteroides infections.
In two of the three cases with sepsis, there was a rapid clinical response to the treatment with oral administration of clindamycin and with intramuscular injections of lincomycin. A case with empyema was treated effectively with a large dose of lincomycin. Lincomycins seem to be the antibiotic of choice for Bacteroides infections.View full abstractDownload PDF (1086K) -
TAKEO MURAKAWA, MINORU NISHIDA1973 Volume 26 Issue 5 Pages 449-453
Published: October 25, 1973
Released on J-STAGE: May 17, 2013
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PHARMACOKINETIC ANALYSIS IN PEDIATRIC FIELDSUSUMU NAKAZAWA, HAJIME SATO, OSAMU WATANABE, KEIZO SADAOKA, NAOMICHI ...1973 Volume 26 Issue 5 Pages 454-458
Published: October 25, 1973
Released on J-STAGE: May 17, 2013
JOURNAL FREE ACCESSSerum concentrationso f DKB (3', 4'-dideoxykanamycin B) intramuscularlya dministeredt o infants and children, were analyzed pharmacokinetically.
The two compartment open model was found in good adaptation to describe the behaviours of DKB after administration to infants and children, as same as in adult patients, reported in the previous paper.
The values of biological half life of DKB in infants and children were 1.2-4 hours, as same as in adult patients. On the other hand, in infants and children, the rate constants for diffusion from administration site to blood, were larger than those in adults.View full abstractDownload PDF (642K) -
NOBUHIKO KOMATSU, NOBORU NAGUMO, KOJI AMEMIYA, MOMOYO KATO, KATSUMASA ...1973 Volume 26 Issue 5 Pages 459-469
Published: October 25, 1973
Released on J-STAGE: May 17, 2013
JOURNAL FREE ACCESSExperimental tuberculosis of mice has been treated with schizophyllan alone and in combination with other antituberculosis drugs.
1) The intraperitoneal administration of 2.5-5.0 mg/kg single dose of schizophyllan every other day for 20 days proved to prolong the life-span of mice infected with Mycobacterium tuberculosis KURONO or SCHACHT strain.
2) The combined therapy with schizophyllan and other antituberculosis drugs (streptomycin, ethambutol and rifampicin) was found to be much more effective than the monotherapy with schizophyllan or the other antituberculosis drug.
3) The histopathological tests of various organs of mice treated with schizophyllan, etalnbutol or schizophyllan-ethambutoclo mbinationw ere carried out. A large number of tubercles were formed and tubercle bacilli diffusely spread in the lung of control group. In the lung of schizophyllan-treated group, the formation of tubercle was few and tubercle bacilli were localized in epitheloid cells which proliferated papillarily in the alveoli; the focal proliferation of RE cells, in which tubercle bacillii were localized, was marked in spleen, liver and lymph nodes.
4) Although moderate activation of RE cells could be observed in ethambutol-treated group, the direct antibacterial effect of ethambutol appears to be highly potentiated in schizophyllan-ethambutol combination group by the strong nonspecific activation of RE cells by schizophyllan.View full abstractDownload PDF (4425K) -
MINORU KOBAYASHI1973 Volume 26 Issue 5 Pages 470-474
Published: October 25, 1973
Released on J-STAGE: May 17, 2013
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KENJI HASHIMOTO, TASUKU SHOJI1973 Volume 26 Issue 5 Pages 475-478
Published: October 25, 1973
Released on J-STAGE: May 17, 2013
JOURNAL FREE ACCESS
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