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Volume 49, Issue 6
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KOJI O'HARA, HAJIME HASHIMOTO1996 Volume 49 Issue 6 Pages 533-543
Published: June 25, 1996
Released on J-STAGE: May 17, 2013
JOURNAL FREE ACCESS -
NAGAO SHINAGAWA, JIRO YURA, TADAO MANABE, KEIJI MASHITA, SYU ISHIKAWA, ...1996 Volume 49 Issue 6 Pages 544-554
Published: June 25, 1996
Released on J-STAGE: May 17, 2013
JOURNAL FREE ACCESSPseudotnonas aeruginosa isolated from surgical infections during the period from July 1982 to June 1995 were investigated in a multicenter study involving 19 hospitals in Japan, and the following results were obtained.
1. Though the isolation rate of P. aeruginosa was not high from primary infections, it was more frequently isolated from postoperative infections throughout the study period. Enterococcus spp., P. aeruginosa and Staphylococcus aureus including MRSA were predominant among postoperative infections. From the postoperative cases that had previous antibiotic treatment, Enterococcus spp., MRSA and P. aeruginosa were more predominantly isolated than from those without previous treatments with antibiotics.
2. Cefozopran, ceftazidime, cefsulodin, aztreonam, carumonam, gentamicin, amikacin and ofloxacin had strong activities against P. aeruginosa. We recognize recently that antibiotic-resistant strains of P. aeruginosa against imipenem and ofloxacin have been increasing year by year.View full abstractDownload PDF (996K) -
III. SECULAR CHANGES IN SUSCEPTIBILITYYOSHIAKI KUMAMOTO, TAKAOKI HIROSE, AKIFUMI YOKOO, YOSHINAO HIKICHI, SH ...1996 Volume 49 Issue 6 Pages 555-657
Published: June 25, 1996
Released on J-STAGE: May 17, 2013
JOURNAL FREE ACCESSSusceptibilities of Enterococcus faecalis, Staphylococcus aureus, Citrobacter spp., Enterobacter spp., Escherichia coli, Klebsiella spp., Proteus mirabilis, Pseudomonas aeruginosa and Serratia spp. isolated from patients with urinary tract infections (UTIs) in 10 hospitals during June 1994 to May 1995 to various antimicrobial agents were compared with those in the same period of previous years according to a classification, uncomplicated UTIs, complicated UTIs without indwelling catheter, and complicated UTIs with indwelling catheter.
No remarkable changes were found in susceptibilities of Citrobacter spp., Enterobacter spp. and Serratia spp. The susceptibilities of E. faecalis to amikacin and quinolones were better than those in 1993. As for S. aureus, susceptible strains to all drugs increased in uncomplicated UTIs. Against E. coli in 1993, the antimicrobial activities of piperacillin, cefotiam and aminoglycosides have decreased, however, in 1994, these activities have turned to the better state. As for Klebsiella spp. susceptible strains to ABPC decreased. The susceptibilities of P. mirabilis to all drugs except minocycline were good. Against P. aeruginosa in 1993, the activities of aminoglycosides have decreased, but, in 1994, these activities have turned to the better state.
These data should be considered in clinical treatment of various urinary tract infections.View full abstractDownload PDF (8004K) -
SHIGERU MUNEMOTO, MARIKO SOMA, EIICHI KURODA, YOSHITAKA HAMADA, MITSUT ...1996 Volume 49 Issue 6 Pages 658-662
Published: June 25, 1996
Released on J-STAGE: May 17, 2013
JOURNAL FREE ACCESSA patient with intracerebral hematoma suffered from postoperative bacterial meningitis. Staphylococcus aureus was found from CSF. The organism was multiple drug resistant and refractory to antibiotics including piperacillin (PIPC), cephalexin (CEX), cefotaxime (CTX), ceftazidime (CAZ) and latamoxef (LMOX). It was susceptible to cefpirome (CPR). Treatment with CPR resulted in clinical improvement associated with clearing of the organism from CSF. Serum level of CPR was high enough and CPR penetration into the CSF was satisfactory. The results suggest that CPR is an extremely effective antibiotic for meningitis caused by CPR susceptible bacteria.
Evaluation of the CPR penetration into the CSF of adult meningitis was rarely reported. The result we obtained was important in the treatment for the adult meningitis.View full abstractDownload PDF (522K)
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