In the present study, the isolation rate of
Clostridium spp. from surgical specimens and its antimicrobial susceptibilities were examined. Last 24 years,
Clostridium spp. was isolated from 65 (1.8%) out of 3,644 specimens from the surgical abdominal infections.
Clostridium spp. was most frequently isolated from secondary peritonitis such as perforated peritonitis, followed by hepato-biliary tract infection. There were 59 cases (90.8%) of mixed infection with
Clostridium spp. and other bacteria. The rate of mixed infection with
Bacteroides spp.(23.6%) was highest, followed by
Escherichia coli (19.7%), other aerobic Gram-negative rods and
Enterococcus spp. Although
Clostridium perfringens was highly sensitive to penicillins, cephems and carbapenems, a small number of
Clostridium spp. other than
Clostridium perfringens were resistant to cephems, erythromycin clindamycin and fosfomycin, respectively.
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