巻号一覧
21 巻, 9 号
選択された号の論文の8件中1～8を表示しています
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SPORANGIOMYCIN, AN ANTIBACTERIAL AGENT ISOLATED FROM PLANOMONOSPORA PARONTOSPORA VAR. ANTIBIOTICA VAR. NOV.J. E. THIEMANN, C. CORONELLI, H. PAGANI, G. BERETTA, G. TAMONI, V. ARI ...1968 年 21 巻 9 号 p. 525-531
発行日: 1968/09/25
公開日: 2006/04/12
ジャーナル フリーA new antibiotic producing actinomyces belonging to the genus Planomonospora is described. Detailed description of its morphological and some of its biochemical characters are given. The antibiotic for which the name sporangiomycin is proposed can be produced successfully under submerged conditions. Sporangiomycin was found to belong to the depsipeptide or peptolide group of antibiotics, and is related to thiostrepton. The antibiotic is highly active in vitro against gram-positive bacteria, and protects mice from streptococcal and diplococcal infections.抄録全体を表示PDF形式でダウンロード (518K) -
SATOSHI OMURA, MICHIKO KATAGIRI, IWAO UMEZAWA, KANKI KOMIYAMA, TOSE MA ...1968 年 21 巻 9 号 p. 532-538
発行日: 1968/09/25
公開日: 2006/04/12
ジャーナル フリーThe relationship between chemical structure and biological activity of leucomycins and their derivatives was examined in vivo and in vitro. The biological activity of Fr-group was higher than that of Ac-group in vitro, but the latter showed higher blood level and lower toxicity than Fr-group. Lengthening of the carbon chain in the O-acyl group at C-4 in mycarose resulted in a marked increase in the biological activity in vitro, with the isovaleryl group having the highest activity. The aldehyde group in the lactone was related to antibiotic activity, but α, β, γ, δ-unsaturated alcohol system at C9- to C12-positions was not important.抄録全体を表示PDF形式でダウンロード (391K) -
ISOLATION, BIOLOGICAL AND CHEMICAL PROPERTIES OF ASCOCHLORIN (STUDIES ON ANTIVIRAL AND ANTITUMOR ANTIBIOTICS. I)GAKUZO TAMURA, SEIKICHI SUZUKI, AKIRA TAKATSUKI, KUNIO ANDO, KEI ARIMA1968 年 21 巻 9 号 p. 539-544
発行日: 1968/09/25
公開日: 2006/04/12
ジャーナル フリーA new antibiotic, ascochlorin, C23H29O4Cl, was obtained from the filter cake of the fermented broth of Ascochyta viciae LIBERT. Ascochlorin inhibits plaque formation of both DNA and RNA viruses in the agar-diffusion plaque inhibition method. However, it showed no antiviral activity by the tube culture method. It showed cytotoxicity to chick embryo fibroblast monolayer and HeLa cells at a concentration of 0.3 meg/ml in tube culture. The anti biotic was obtained in two forms, the physical and chemical properties of which are described.抄録全体を表示PDF形式でダウンロード (356K) -
KIMIHIKO ABE, TOJU HATA1968 年 21 巻 9 号 p. 545-550
発行日: 1968/09/25
公開日: 2006/04/12
ジャーナル フリーKitasatoa kauaiensis, a new species of the genus Kitasatoa, belonging to the family Streptoplanaceae, produces 3 kinds of antibiotics in a culture broth. These antibiotics were identified as chloramphenicol, bottromycin and fradicin based on their physico-chemical and biological properties. A new differential bioassay method for chloramphenicol and bottromycin produced in the same culture broth was established.抄録全体を表示PDF形式でダウンロード (295K) -
PREPARATION OF 3-ACYLAMIDO-4-HYDROXY-8-METHYL-7-[3-O-(5-METHYL-2-PYRROLYLCARBONYL)NOVIOSYLOXY] COUMARINSJ.G. KEIL, I.R. HOOPER, M.J. CRON, O.B. FARDIG, D.E. NETTLETON, F. A. ...1968 年 21 巻 9 号 p. 551-566
発行日: 1968/09/25
公開日: 2006/04/12
ジャーナル フリーThe ditetrahydropyranyl ether of coumermycin A1 was prepared and converted to a series of new derivatives by an acyl interchange reaction. The mechanism of this interesting and useful reaction is discussed. All of the 67 semisynthetic coumermycins described are active antibiotics, and several of them show desirable changes in physical properties from those of the parent coumermycin A1. Comparative activities against Staphylococcus aureus Smith are reported.抄録全体を表示PDF形式でダウンロード (961K) -
SEIGO TAKASAWA, RYOZO UTAHARA, YASUSUKE OSATO, KENJI MAEDA, HAMAO UMEZ ...1968 年 21 巻 9 号 p. 567
発行日: 1968/09/25
公開日: 2006/04/12
ジャーナル フリーPDF形式でダウンロード (75K) -
CHEMICAL STRUCTURES OF ACTINOMYCIN S2 AND S3MINORU FURUKAWA, ATSUO INOUE, KAZUO ASANO, JUNICHI KAWAMATA1968 年 21 巻 9 号 p. 568-570
発行日: 1968/09/25
公開日: 2006/04/12
ジャーナル フリーPDF形式でダウンロード (171K) -
JIRO SUZUKI, MAKOTO HORI, HAMAO UMEZAWA1968 年 21 巻 9 号 p. 571-573
発行日: 1968/09/25
公開日: 2006/04/12
ジャーナル フリーPDF形式でダウンロード (201K)
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