Cirramycin A, a macrolide antibiotic, has been found to consist of one major (A
1) and several minor components (A
2, A
3, A
4 and A
5). The majoractive substance, cirramycin A
1 (C
31H
51NO
10), was isolated as a single component and characterized in detail. It has a strong ultraviolet absorption peak at 241mμ and its chromophore is suggested to be an α, β-unsaturated γ, δ-depoxide carbonyl system. Cirramycin A
1 contains the basic sugar mycaminose but lacks a neutral sugar in the molecule.
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