Japanese Journal of Allergology

[title in Japanese]

Article type: Cover
1973 Volume 22 Issue 12 Pages Cover13-
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.Cover13

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[title in Japanese]

Article type: Cover
1973 Volume 22 Issue 12 Pages Cover14-
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.Cover14

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[title in Japanese]

Article type: Bibliography
1973 Volume 22 Issue 12 Pages Misc3-
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.Misc3

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Serological Studies on Lysozyme (3) : Immunoelectrophoretic Studies on Human Saliva

Shiro Takada

Article type: Article
1973 Volume 22 Issue 12 Pages 713-721
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.713

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Saliva proteins were analysed immunoelectrophoretically with anti-human saliva rabbit serum. Seven precitin lines were found, and one of which might be due to IgA as same the component in serum. Among other 6 lines, that of amylase was most characteristic and prominent, and the precipitin was identified with enzymatic technique. Other saliva-specfic components, a cathodal component (CC) and double component (DC) were identified. Precipitin line of lysozyme was undetectable. However, in the system of egg white and its antibody, the pecipitin line was determined with bacteriolytic activity. Immunoelectrophoresis of saliva of partients with recurrent aphthous stomatitis and Behcet's disease revealed that amylase activity in the latter saliva decreased but not a change was observed in the former. It is also useful to diagnose whether the fluid of retention cysts in oral surgery is originating from saliva or serum.

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Study on Surface Immunoglobulin Bearing Cell of Human Peripheral Blood Lymphocytes

Shinya Tada, Yasunari Nakata, Shigeru Arimori

Article type: Article
1973 Volume 22 Issue 12 Pages 722-727,757-75
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.722

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A few reports has been appeared concerning on a human circulating B cells; the lymphocytes on which surfaces bound immunoglobulins. These reports covered mainly a special diseasers such as chronic lymphocytic leukemia, acute lymphocytic leukemia, Hodgkin's disease and congenital immunodeficiency syndromes. The percentages of B cell in circulating lymphocytes of the parients with autoimmune diseases and some hematological disorders were examined in this paper. The Conray 400-Ficoll technique was used for separation of circulating lymphocytes. This lymphocytes had 98% purity and 100% viability. Using the membrane immunofluorescent technique, surface immunoglobulin bearing cell (SIBC) was determined by the Nikon fluoromicroscope. SIBC were able to classify into three types; caping form, and faint form, according to their staining patterns. Caping and ring form staining were considered to be specific for SIBC, and calcuated their percentages against the circulating lymphocytes. In normal subjects the percentage of SIBC (IgG, A, M) was 20.7%, SIBC (IgG) 18.8% and SIBC (IgM) 9.3%. Increased SIBC (IgG, A, M) was observed in the patients with polymyositis and chronic lymphocytic leukemia and decreased in the patients with myasthenia gravis. SIBC (IgM) did not show remarkable changes in these diseases examined. After thymectomy, SIBC (IgG, A, M and IgG) increased significantly than before thymectomy in the parients with myasthenia gravis, having no remarkable changes in SIBC (IgM).

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Serum Prostaglandin Levels in Bronchial Asthma

Toshikazu Nemoto, Hideo Aoki, Aiko Ike, Kuniko Yamada, Tadanori Kondo, ...

Article type: Article
1973 Volume 22 Issue 12 Pages 738-734,758
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.738

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1. Both PGF and PGE values were significantly higher in asthmatics than in normal controls. 2. Among asthmatics, most intractable patients had higher PGF and lower PGE values than tractable partients. 3. The ratio PGF/PGE value showed significant differences among the three groups: tractable patients showed higher value than normal subjects and the intractable patients showed the highest values.

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Study on the Most Adequate Dosis of the Aerosol Bronchodilator (Fenoterol) in Patient with Chronic Obstructive Lung Disease

Yukio Goto, Yutaka Kimura, Takako Tsuda

Article type: Article
1973 Volume 22 Issue 12 Pages 735-744,758
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.735

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In order to determine the most adequate does of the aerosol of fenoterol (Berotec[○!R]:a bronchodilator), the effect of 0.25-5.0 mg/ml of fenoterol was compared with that of 3 mg/ml of isoproterenol and negative placebo (physiologic saline). The improvement ratio of the respiratory function after inhalation of each drug by intermittent positive pressure breathing was expressed by the mean value of four possible classification. The results of spirometry clearly show that fenoterol improves markedly the obstructive respiratory disturbance and that the increase of the ventilatory function appears to depend on the dose. Some few patients complained of slight palpitation with the inhalation of 1.25-1.5 mg/1.0 ml of the drug, but the inhalation of 1.5 mg/1.0 ml or less fenoterol did increase heart rate on the average. The date of spirometry, peak expiratory flow rate, candle test and the respiratory resistance indicate that increasing dosis of fenoterol produces more effective bronchodilation and that 1.0-1.5 mg/1.0 ml of fenoterol is the adequate dosage range which is more effective than 3.0 mg/1.0 ml of isoproterenol and having no side effect. The duration of effect of fenoterol appears to be 1.5-2.5 hours at the shortest.

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Studies on in Vitro Release of Histamine in Asthmatic Patients with Reference to Mechanism of Hyposensitization Therapy

Hiroshi Saito

Article type: Article
1973 Volume 22 Issue 12 Pages 745-756,759
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.745

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A study was attempted to clarify the mechanism of hyposensitization therapy with in vitro release of histamine, threshold tite of the intradermal test, serum IgE levels and basophil counts in peripheral blood. The following results were obtained. 1) There was a different pattern between healthy persons and asthmatics in diurnal variation of plasma histamine levels. 2) The Blood of non-allergic individuals showed no histamine release with house dust (HD) antigen. But the blood of HD sensitive asthmatics showed obvious histamine release with HD antigen. There was a correlation between minimum effective dosis (MED) of HD antigen and histamine release. 3) Histamine release in HD sensitive asthmatics was not inhibited with steroid hormone. 4) In favourable cases, histamine release was inhibited about 3 to 4 monthes after commencement of hyposensitization therapy. At this time, MED of HD antigen rised and serum IgE level decreased. On the contrary, histamine release was not inhibited in unfavourable cases. 5) Basophil counts in peripheral blood did not show a certain tendency during hyposensitization therapy, but increased significantly during period of frequent paroxysms. 6) Basophil and eosinophil counts in peripheral blood and histamine release increased just before paroxysm, but decreased during paroxysm.

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[title in Japanese]

Article type: Bibliography
1973 Volume 22 Issue 12 Pages 757-759
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.757

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[title in Japanese]

Article type: Appendix
1973 Volume 22 Issue 12 Pages 760-763
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.760

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[title in Japanese]

Article type: Appendix
1973 Volume 22 Issue 12 Pages 764-
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.764

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[title in Japanese]

Article type: Index
1973 Volume 22 Issue 12 Pages 765-769
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.765

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[title in Japanese]

Article type: Appendix
1973 Volume 22 Issue 12 Pages 770-773
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.770

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[title in Japanese]

Article type: Cover
1973 Volume 22 Issue 12 Pages Cover15-
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.Cover15

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[title in Japanese]

Article type: Cover
1973 Volume 22 Issue 12 Pages Cover16-
Published: December 30, 1973
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.22.Cover16

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