All issues
Volume 24, Issue 10
Displaying 1-12 of 12 articles from this issue
- |<
- <
- 1
- >
- >|
-
Article type: Cover
1975 Volume 24 Issue 10 Pages Cover5-
Published: October 30, 1975
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (34K) -
Article type: Cover
1975 Volume 24 Issue 10 Pages Cover6-
Published: October 30, 1975
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (34K) -
Article type: Bibliography
1975 Volume 24 Issue 10 Pages Misc2-
Published: October 30, 1975
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (231K) -
Yasuo Horiuchi, Itaru AndoArticle type: Article
1975 Volume 24 Issue 10 Pages 695-702,733
Published: October 30, 1975
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSAlthough histamine is not the only mediator of atopy, assay of histamine level in blood appears to be useful for studying atopic reaction in the laboratory. The changes of blood histamine levels were studied in asthmatic children. The following results were obtained. 1. Mean histamine level in the sera from 10 asthmatic children was 0.065±0.012μg/ml. 2. The diurnal variation of mean value in 11 asthmatic children was 0.058±0.009μg/ml at a.m. 9.00, 0.055±0.009μg/ml at p.m. 3.00 and 0.065±0.012μg/ml at p.m. 9.OO respectively. 3. Mean blood histamine level before and after exercise in 12 asthmatic children was 0.059±0.016μg/ml and 0.061±0.014μg/ml respectively. 4. The average amount of blood histamine of 10 asthmatic children given with hyposensitization therapy of house dust during 10 months to 3 years was 0.035±0.006μg/ml. 5. The mean content of histamine in the sera from 5 asthmatic children following orally administered corticosteroid was 0.045±0.010μg/ml.View full abstractDownload PDF (971K) -
Yukinobu Ichikawa, Kenji Koriyama, Shigeru Arimori, Hidehiro Kobashi, ...Article type: Article
1975 Volume 24 Issue 10 Pages 703-708,733-73
Published: October 30, 1975
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSIt had been reported that a higher frequency of the thymic abnormalities including thymoma and/or thymic hyperplasia with germinal centers and the effectiveness of thymectomy could be demonstrated in the patients with myasthenia gravis. The relationship between these thymic abnormalities and clinical features in myasthenia gravis, however, has not been clarified satisfactorily yet. Twenty-two thymuses obtained from myasthenic patients, who had undergone thymectomy, were investigated histologically. The hyperplastic thymuses with germinal centers were found in 52.6% of all cases including non-thymomatous regions in the thymuses with thymoma, and were observed in higher per centages in the younger myasthenic patients. The density of germinal centers was higher in the thymuses of clinically severe myasthenic patients, especially of thymomatous patients, whose thymuses had numerous germinal centers in all cases, than of the ocular myasthenia or nonthymomatous patients. These patients whose thymuses could be demonstrated numerous germinal centers deteriorated their clinical symptomes even after the thymectomy, who were followed by the improvement with the administrations of prednisolone. The older patients were, the more frequently Hassall's corpuscles in the thymic medulla were detected, although the clinical features were scarcely related with the density of Hassall's corpuscles. Of twenty-two patients, eight had thymomas; six of them were lympho-epithelial cell types, one was spindle cell type, and one was lymphocytic cell type. These results suggested that the density of germinal centers was one of the most important factors correlating with the clinical features and the responsiveness to the thymectomy or steroid therapy in the myasthenia patients.View full abstractDownload PDF (1117K) -
Tsunesuke Tomoda, Takashi Kageyama, Yutaka Oi, Shiro NagaoArticle type: Article
1975 Volume 24 Issue 10 Pages 709-712,734
Published: October 30, 1975
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSIt was demonstrated that the mixing of a small amount of serologically active tuberculoproteins with citrated blood from tuberculous patients markedly changed its erythrocyte sedimentation rate (ESR). The protein sample was isolated from mechanically disintegrated human tubercle bacilli in native and consequently in serologically active state, as frequently reported. This effect was studied in 102 patients with pulmonary tuberculosis with reference to their clinical condition. The mixing of protein caused elevation of the ESR in many patients with pulmonary tuberculosis. This action could not be recognized for the protein such as PPD, CRP. On the contrary the same procedure lowered the ESR of the blood from patients at the onset of very active tuberculosis. Similar but much milder effect was noted with blood from hopeless cases. In nontuberculous patients, this effect could not be observed. This peculiar phenomenon was explained as that large-sized antigen-antibody complexes in the circulation should enhance the rouleaux arrangement of human red cells and consequently accelerate rapid setting of them in the plasma.View full abstractDownload PDF (577K) -
Koji Tateno, Shigeki Nakajima, Masao Todokoro, Tatsuo Matsumura, Tomok ...Article type: Article
1975 Volume 24 Issue 10 Pages 713-725,734-73
Published: October 30, 1975
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSA patient with bronchial asthma who became free from attacks for several months with an elimination diet developed nearly fatal attacks in the spring. This case stimulated the authors to study the allergenicity of Meadow Foxtail pollen and asthma since it was at the flowering season of the Meadow Foxtail when this patient suddenly worsened. In order to determine the relationship between bronchial asthma and Meadow Foxtail, the following investigation was carried out. On interactaneous testing, 42 of 103 asthmatic children (29%) showed a positive reaction. On the other hand, 4 of 207 healthy children (2%) showed a positive reaction. P-K testing revealed positives in 2 of 4 cases. As a provocative test, a reduction of 15% or more in the P.E.F.R. and/or asthmatic symptoms including wheezing were considered positive. As a result, 2 tested patients reacted positively to Meadow Foxtail pollen extract administered by inhalation. From these results, it is concluded that Meadow Foxtail pollen is one of the significant allergens in bronchial asthma in Japan.View full abstractDownload PDF (1855K) -
Takahiko KajiArticle type: Article
1975 Volume 24 Issue 10 Pages 726-732,735
Published: October 30, 1975
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESST and B cells were counted in the peripheral blood of patients with myasthenia gravis. Lymphocytes binding more than 3 sheep red blood cells were counted as T cells, and surface Ig bearing lymphocytes detected by a standard immunofluorescence method were determined as B cells. The percentage of T cells was 49.1±11.3 (mean ± s.d.) in 30 patients with myasthenia gravis and 40.1±5.8% in healthy individuals, and absolute counts of T cells were slightly higher but not significantly as compared with normal individuals. On the other hand, the percentage of B cells was 25.2±8.6% in the patients with myasthenia gravis and 23.1±7.1% healthy individuals. Higher scores of T cells were observed in the patients in the more severe clinical status as estimated by Osserman's classification. Mean values of percentage of T cells was higher in the patients with thymoma than in those without thymoma. Mean values of percentage of T cells was higher in the antimuscle antibody possitive patients than in those negative.View full abstractDownload PDF (1081K) -
Article type: Bibliography
1975 Volume 24 Issue 10 Pages 733-735
Published: October 30, 1975
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (211K) -
Article type: Appendix
1975 Volume 24 Issue 10 Pages 736-
Published: October 30, 1975
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (184K) -
Article type: Cover
1975 Volume 24 Issue 10 Pages Cover7-
Published: October 30, 1975
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (31K) -
Article type: Cover
1975 Volume 24 Issue 10 Pages Cover8-
Published: October 30, 1975
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (31K)
- |<
- <
- 1
- >
- >|