All issues
Volume 25, Issue 11
Displaying 1-13 of 13 articles from this issue
- |<
- <
- 1
- >
- >|
-
Article type: Cover
1976 Volume 25 Issue 11 Pages Cover9-
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (37K) -
Article type: Cover
1976 Volume 25 Issue 11 Pages Cover10-
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (37K) -
Article type: Bibliography
1976 Volume 25 Issue 11 Pages Misc3-
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (283K) -
Akira Ozawa, Muneo Ohkido, Kan Niizuma, Itsuro Matsuo, Masao Nakano, K ...Article type: Article
1976 Volume 25 Issue 11 Pages 751-757,796
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSEighty-three unrelated Japanese patients with atopic dermatitis and sixty-six normal, healthy, unrelated Japanese controls were tissue typed using the 6th International histocompatibility workshop antisera. Two patients groups were included in this study: thirty-six atopic dermatitis with asthma bronchiale and forty-seven atopic dermatitis without asthma bronchiale. HLA-BW40 (p<0.005) from the Locus B were found to occur with increased frequency in 83 patients with atopic dermatitis. But HLA-BW15 was not found in 83 patients with atopic dermatitis as compared with 20% of 66 controls. But there was not a significant difference between the two groups of atopic dermatitis in the frequency of HLA-BW40. The frequency of HLA-B12 was significantly (p<0.05) higher (27.78%) in patients with asthma bronchiale than in those without asthma bronchiale (8.51%). Though no linkage between any group of atopic dermatitis with or without asthma bronchiale and HLA was observed in twenty-one families, it ws found that those diseases have been susceptible to HLA.View full abstractDownload PDF (945K) -
Shinya Suzuki, Masanori Miyoshi, Shuzo Hirakawa, Mikio Mitsunaga, Kan ...Article type: Article
1976 Volume 25 Issue 11 Pages 758-764,796-79
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSSera from 11 of 14 Hashimotos patients showed anti-thyroblobulin antibodies that were cytophilic for human monocytes. These serum cytophilic antibodies permited normal monocytes to bind human thyroglobulin coated erythrocytes(Tg-RBC). Isolated monocytes from normal donors incubated with Hashimoto's sera for 60min at 10℃ obtained the ability to form rosettes with Tg-RBC. The reaction was immunologically specific and did not bind human albumin coated erythrocyte (HSA-RBC). The addition of a small amount of free thyroglobulin to the medium inhibited competitively the binding of Tg-RBC to monocytes. The cytophilic antibody titer expressed by % binding of Tg-RBC to sensitized monocytes ranged from 2.0 to 40.0% and correlated roughly with the hemagglutinating antibody titer (TRC titer). Some sera (4 of 14 cases) with high TRC titer showed weak cytophilic binding. A discrepancy between cytophilic antibody activity and hemagglutinating antibody titer was also present in hyperimmune serum of habbit immunized against human thyroglobulin. The reason of this discrepancy is not known at present. Sensitization of monocytes in vivo with the cytophilic anti-Tg antibody might be responsible for the binding of Tg-RBC by isolated monocytes from patients with Hashimotos thyroiditis.View full abstractDownload PDF (1645K) -
Hirofumi KawashimaArticle type: Article
1976 Volume 25 Issue 11 Pages 765-773,797
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSIn an attempt to determine proper dose and route of the administration of aminophyline, plasma theophylline concentration was followed up in 20 asthmatics and 6 controls after aminophylline, was given by oral administration, intravenous injection, intravenous drip infusion, or by the combination of them. Plasma theophylline concentration was measured by Schack and Waxler's method. No significant differences were seen between the plasma theophylline concentrations in asthmatics and those in controls after the administration of aminophylline. The plasma theophylline reached to the highest concentration rapidly after an intravenous injecton of aminophylline, where as it reached the peak gradually in 3 to 4 hours affter intravenous infusion or oral administration of aminophylline. The peak plasma theophylline concentrations following intravenous injection, drip infusion, intravenous injection plus drip infusion and oral administration were 6.91, 3.86, 7.53, 2.87μg/ml respectively. The half-time of plasma theophylline concentrations were 3 hours after an intravenous injection of aminophylline and 6 to 9 hours after its intravenous injection plus drip infusion. The appropriate administration of aminophylline in the first day of asthma attack is considered to be 250mg by intravenous injection together with another 250mg by drip method, followed by 250mg drip infusion every 6 hours.View full abstractDownload PDF (1189K) -
Teizo TayaArticle type: Article
1976 Volume 25 Issue 11 Pages 774-783,797-79
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSThe clinical effects of immunotherapy and some pathophysiological studies were performed on "Konjac asthma" and on "sericultural asthma" which were representative occupational bronchial asthma in Japan. Results were as follows. 1) The patients with Konjac asthma showed 11 immediate asthmatic response out of 18 cases (61.1%) on their provocative inhalation tests, others showed dual responses. (immediate and late response). In RAST test, all 9 cases examined showed more than one score positive results, although grade of score did not pararell with their clinical severity. Precipitins was found 16 out of 24 cases (66.7%) in patients with konjac asthma. But, 6 out of 12 cases (50.0%) also showed precipitins in normal subjects exposed with the antigen. 2) In Sericultural asthma, 19 out of 23 cases (82.6%) showed immediate asthmatic responses in provocative inhalation tests, and 4 cases (17.4%) showed dual responses. Positive Prausnitz-Kustner reaction was detected in all 10 cases. 3) After immunotherapy (hyposensitization therapy by the proper allergen), 51.4% of Konjac asthmatic patients obtained good relief. On the contrary, 78.1% of sericultural asthmatic patients obtained it. 4) Increases of blocking antibody titer after immunotherapy were observed in both asthma, but there was not a good correlation between clinical results and blocking antibody titer.View full abstractDownload PDF (1513K) -
Takeo Yoshinouchi, Tetsuki Amano, Yasuhiko Mitsuhashi, Hiroto Miyashim ...Article type: Article
1976 Volume 25 Issue 11 Pages 784-790,798
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSThe relationship between the classical complement pathway and the alternative complement pathway was in 20 systemic lupus erythematosus (SLE) patients by measuring the serum chemotactic activity. The chemotactic activity was investigated by activation of the classical or alternative complement pathway. The classical pathway was activated by aggregated human Fr. II and the alternative pathway was activated by zymosan. The individual patient chemotactic index (CI) was expressed as a percentage of the paired normal control. The classical pathway-chemotactic index (CCI) was correlated with CH_<50>, β_<1C>/_<1A> globulin (C3) and β_<1E> globulin (C5), but not with β_<1E> globulin (C4). The alternative pathway-chemotactic index (ACI) was not correlated with CH_<50>, β_<1E> globulin, β_<1C>/_<1A> globulin and β_<1F> globulin. CCI was positively correlated with ACI. Both indices were low but CCI was more depressed than ACI. The findings of study suggest that the alternative pathway remains enough even if the classical pathway is consumed in SLE patients, and that the alternative pathway may be activated by the positive feedback mechanism of the complement system.View full abstractDownload PDF (701K) -
Hiroshi Yoshida, Reiji Kasukawa, Takeo Yoshida, Karou NakamuroArticle type: Article
1976 Volume 25 Issue 11 Pages 791-795,798-79
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSThe surface antigens of human platelets were studied by means of cytolysis test in agarose gel and mixed agglutination test. Rabbit antisera to cultured human nucleated cells (AV_3) reacted with all specimens of platelet taken from 5 individuals as well as with the AV_3 cells. The antibody titers against platelets were ranging from 12800 to 51200 in the mixed agglutination test and from 80 to 320 in the thrombocytolysis test. These results could indicate that the anti-AV_3 antibody detected the surface antigens present commonly on platelets and AV_3 cells. The antigen distribute widely on the surface of nucleated cells and platelets as species specific antigens. Subsequently, rabbit antisera to two subcomponents of surface antigens of human cells, HLA-11000 Dalton fraction prepared by Tanigaki et al. and β_2-microglobulin, were tested against platelets. The antibody titers of both sera were ranging from 12800 to 51200 in the mixed agglutination test and from 80 to 320 in the thrombocytolysis test. In order to clarify the correlation among the species specific antigens, the antigen of HLA-11000 Dalton fraction and β_2-mioroglobulin, displacement tests were performed. The antigenicity of HLA-11000 Dalton fraction and that of β_2-microglobulin seemed to be identical or very close, and β_2-microglobulin was considered to be one of the complexes of species specific antigens associated with the surface membrane of platelets and nucleated cells.View full abstractDownload PDF (727K) -
Article type: Bibliography
1976 Volume 25 Issue 11 Pages 796-799
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (273K) -
Article type: Appendix
1976 Volume 25 Issue 11 Pages 800-802
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (208K) -
Article type: Cover
1976 Volume 25 Issue 11 Pages Cover11-
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (40K) -
Article type: Cover
1976 Volume 25 Issue 11 Pages Cover12-
Published: November 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (40K)
- |<
- <
- 1
- >
- >|