Japanese Journal of Allergology
Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884
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Volume 29, Issue 2
Displaying 1-11 of 11 articles from this issue
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  • [title in Japanese]
    Article type: Cover
    1980 Volume 29 Issue 2 Pages Cover13-
    Published: February 28, 1980
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.29.Cover13
    JOURNAL FREE ACCESS
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  • [title in Japanese]
    Article type: Cover
    1980 Volume 29 Issue 2 Pages Cover14-
    Published: February 28, 1980
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.29.Cover14
    JOURNAL FREE ACCESS
    Download PDF (31K)
  • [title in Japanese]
    Article type: Bibliography
    1980 Volume 29 Issue 2 Pages Misc5-
    Published: February 28, 1980
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.29.Misc5
    JOURNAL FREE ACCESS
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  • [title in Japanese]
    [in Japanese]
    Article type: Article
    1980 Volume 29 Issue 2 Pages 53-62
    Published: February 28, 1980
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.29.53
    JOURNAL FREE ACCESS
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  • COLD ACTIVATION OF COMPLEMENT : Quantitative Estimation of Anti-IgG Reactive with Insolubilized Human IgG in Sera with Cold Activation of Complement
    Shuhei Takemura, Hiroki Tagami, Yoshikazu Wakamatsu, Yasumasa Furukawa ...
    Article type: Article
    1980 Volume 29 Issue 2 Pages 63-67
    Published: February 28, 1980
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.29.63
    JOURNAL FREE ACCESS
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    The factors responsible for cold activation of complement (CAC) have been reported to be cryoglobulin and soluble cryoglobulin-like substances in individuals without cryoglobulin. To investigate the participation of anti-IgG in CAC, anti-IgG was measured in sera with CAC and without CAC, using insolubilized human IgG. All sera with CAC and some of sera without CAC inchronic liver diseases revealed high anti-IgG. Furthermore, comparing the anticomplement activity at 4℃ of anti-IgG adsorbed and non-adsorbed serum, the former revealed much lower anticomplement activity than the latter. Our findings suggest that anti-IgG takes part in the mechanism of CAC. Considering that cryoglobulin often shows anti-IgG (rheumatoid factor) activity, these data suggest that a soluble cryoglobulin-like substance is one of the responsible factors for CAC.
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  • BRONCHIAL REACTIVITY IN ASTHMATIC CHILDREN : II. Bronchial Reactivity to Acetylcholine and House Dust Extract
    Yoshiaki Inagaki, Akira Kanai, Masanori Yamada, Masami Yoshida, Masano ...
    Article type: Article
    1980 Volume 29 Issue 2 Pages 68-73
    Published: February 28, 1980
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.29.68
    JOURNAL FREE ACCESS
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    In 77 children with broncial asthma, inhalation tests with acetylcholine and house dust extract were carried out. 1) The levels of respiratory threshold of acerylcohline were less than 97×2^7μg in 88% of the asthmatics and 97×2^7μg or more in non-asthmatics. 2) There was apparently no correlation between respiratory threshold of acetylcholine and the decreases of FEV_<1.0> with house dust extract, but lower levels of respiratory threshold were found with house dust extract in asthmatics with positive than in those with negative response (p<0.005). 3) Regarding the late response in the inhalation tests with house dust extract, lower levels of respiratory threshold of acerylcholine were observed in the positive than in the negative group (0.01<p<0.025). 4) there was no correlation between respiratory thresholds of acerylcholine and the age at the onset of asthma or the period of the disease. 5) Severe asthmatics were likely to have lower levels of respiratory threshold of acetylcholine in comparison with the moderate or mild asthmatics (p<0.1). 6) There was a significant correlation between the levels of respiratory threshold of acetylcholine and histamine (r=0.5, p<0.005).
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  • DIAGNOSIS OF ASTHMA DUE TO MOLD ANTIGENS : Comparison Among the Results of Skin Test, Radioallergosorbent Test, Conjunctival and Bronchial Provocation Test
    Kazuo Akiyama, Yasuo Yui, Takao Shida
    Article type: Article
    1980 Volume 29 Issue 2 Pages 74-84
    Published: February 28, 1980
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.29.74
    JOURNAL FREE ACCESS
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    Intradermal skin tests, radioallergosorbent test (RAST) conjunctival and bronchial provocation tests with crude Candida albicans, Aspergillus fumigatus and Alternarea kikuchiana antigens and radioimmunosorbent test (RIST) were performed in patients with asthma. Then, the correlations between each other were studied. 1) Conventional RAST methods using paper discs activated by BrCN, coupled with crude mold antigens, could be used to measure the specific IgE antibodies. The correlations and agreements between RAST and the other methods with mold antigens were as same as those with other antigens including pollens and mite. 2) In place of bronchial provacation test, conjunctival provocation test seemed to be the best, RAST in second and intradermal skin test in third. 3) No significant correlation was obrained between total IgE levels in serum and the threshold of the intradermal skin reaction. Low but significant correlation was obtrained between total IgE levels in serum and RAST.
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  • OCCUPATIONAL ASTHMA OF NON-WORKER : Occupational Asthma in those Who Are Not Engaged in the Job
    Etsushi Okumura
    Article type: Article
    1980 Volume 29 Issue 2 Pages 85-91
    Published: February 28, 1980
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.29.85
    JOURNAL FREE ACCESS
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    We have experienced asthmatic patients who were sensitized with the allergens related to paticular occupations but themselves not engaged in the job. We propose the classification of such kind of asthma as follows and show the number of cases appeared in Japanese bibriography which belonged to each group. 1) Patients living in a small manufactory in their own houses: 19 persons. 2) Patients living around industrial areas: 23 persons. 3) Patients in worker's families: 1 persons. Classificaion: Type A: Occupational asthma in workers. Type B: Occupational asthma in those who are not engaged in the particular job. b_1: Patients living in a manufactory in their own houses.b_2: Patients living in vicinity of industrial areas. b_3: Patients are one of the worker's families.
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  • EFFECT OF IMMUNOSUPPRESSANTS ON IN VITRO IMMUNOGLOBULIN PRODUCTION OF HUMAN LYMPHOCYTES : I. Different Effects of Various Immunosuppressants on Immunoglobulin Production
    Hiroyuki Ogawa, Takehiko Sakurami, Hiroo Imura
    Article type: Article
    1980 Volume 29 Issue 2 Pages 92-98
    Published: February 28, 1980
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.29.92
    JOURNAL FREE ACCESS
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    Normal human peripheral lymphocyte suspensions were incubated for 7 days at 37℃ with various concentrations of immunosuppressants. Then, the amount of immunoglobulin (Ig) secreted into the culture medium and the ^3H-thymidine (^3H-TdR) incorporation rate into DNA were quantitated. 1) ^3H-TdR incorporaion rates were significantly decreased in presence of 0.01μg/ml glucocorticoids (GC; hydrocortisone and prednisolone) compared with controls. In contrast, increased Ig formation was observed in the presence of 0.01-1μg/ml of GC. This discrepancy may be due to the different susceptibility of lymphocyte subpopulations to GC. 2) Other immunosuppressants such as cyclophosphamide, 6-mercaptopurine, melphalan and mitomycin C suppressed both Ig formation and ^3H-TdR incorporation in parallel with the elevationof the concentrations. The in vitro effects of these immunosuppressants, except for cyclophosphamide, were correlated with therapeutic doses observed in vivo.
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  • [title in Japanese]
    Article type: Appendix
    1980 Volume 29 Issue 2 Pages 99-102
    Published: February 28, 1980
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.29.99
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  • [title in Japanese]
    Article type: Cover
    1980 Volume 29 Issue 2 Pages Cover15-
    Published: February 28, 1980
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.29.Cover15
    JOURNAL FREE ACCESS
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