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Volume 34, Issue 6
Displaying 1-14 of 14 articles from this issue
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Article type: Cover
1985 Volume 34 Issue 6 Pages Cover25-
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (192K) -
Article type: Cover
1985 Volume 34 Issue 6 Pages Cover26-
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (192K) -
Article type: Appendix
1985 Volume 34 Issue 6 Pages App4-
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
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Article type: Bibliography
1985 Volume 34 Issue 6 Pages Misc9-
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (247K) -
Kensei Naito, Yoshio Senoh, Hitoshi Toda, Keizo Koyama, Shigenobu Iwat ...Article type: Article
1985 Volume 34 Issue 6 Pages 341-350
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSIn cases of nasal allergy, 27 untreated and 11 treated by specific hyposensitization, nasal resistance was measured by rhinomanometry (combined, anterior and oscillation method) before and after nasal provocation. The anterior method seemed to be the most convenient and suitable for the assesment of nasal resistance by repeated tests during 60 min. In untreated cases, unilateral nasal obstruction was commonly seen but total nasal obstruction was not found out. 15 min after provocation, resistance increased in 22 cases, and further increased after 60 min in 9 cases while it decreased in the other 13. The group with gradual increase of nasal resistance consisted mainly of patient with non-seasonal allergy and those with a long history. Changes in resistance on the provocated side tended to have an inverse effect on the resistance of the other side. There was no correlation between changes in nasal resistance and changes in the amount of eosinophiles in nasal mucus. We consider that measurment of nasal resistance before and after provocation is a valid indicator for the efficiency of specific hyposensitization.View full abstractDownload PDF (1129K) -
Toshihiko Hori, Hiroya OhyamaArticle type: Article
1985 Volume 34 Issue 6 Pages 351-358
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSEleven cases of occupational apple and pear pollinosis were studied. All the patients have been engaged in growing both apples and pears and were considered to be sensitized to apple and pear pollen. Studies on cross-allergenicity by RAST inhibition have revealed that Japanese apple pollen and Japanese pear pollen have a strong cross-allergenicity, whereas they show individual allergenicity against Japanese Cedar pollen and orchard grass pollen. In Matsukawa town, due to an increased exposure to pollen by cultivation of both apples and pears, the rate of occurrence of occupational pollinosis may possibly be higher than that of other regions where only apples or pears are cultivated. Further investigation on this problem is needed.View full abstractDownload PDF (824K) -
Kazuharu Tsukioka, Shigeru Hirono, Kazumitsu IshikawaArticle type: Article
1985 Volume 34 Issue 6 Pages 359-364
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSSix cases of peach (Prunus persica) pollinosis occured in peoples who have not been engaged in growing peaches were studied. Five of the cases were male, aged 21, 25, 27, 42 and 44 years old, and one was a 15-year-old female. They have all lived for between 5 and 42 years in one of the regions where many peach trees are grown. The results of intradermal tests using peach pollen extract were positive in five cases and doubtful in one. Nasal and bronchial provocation tests and the Prausnitz-Kustner test using peach pollen extract were done in three cases respectively, and these tests were positive in all of three cases tested.View full abstractDownload PDF (842K) -
Akihiro Morikawa, Hideo Arai, Hiroyuki Mochizuki, Kenichi Tokuyama, Ma ...Article type: Article
1985 Volume 34 Issue 6 Pages 365-370
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSTheophylline concentrations were measured by the apoenzyme reactivation system and the results were compared with those obtained by high performance liquid chromatography (HPLC) and substrate labelled fluorescent immunoassay (SLFIA). The results obtained by the above three methods were well compatible with each other. Furthermore, the capillary tube method produced results quite parallel to the venous blood method, and the former is very useful for frequent measurement of theophylline concentration, especially in children with asthma. Further, free theophylline concentration was measured by ARIS using ultrafilter cones (Amicon MPS-3), revealing that theophylline in serum consists of 63% free theophylline and 37% protein binding theophylline under the condition of pH 7.45-7.55.View full abstractDownload PDF (641K) -
Hiroshi Sato, Michiko Ishizaki, Hiroshi Yasueda, Yasuo Yui, Takao Shid ...Article type: Article
1985 Volume 34 Issue 6 Pages 371-378
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSThe present study was carried out to investigate the immunological role of α-Streptococcus (α-st) in bronchial asthma by employing radioallergosorbent test (RAST), bronchial provocation test (BPT) and skin test. The supernatant obtained from sonicate of α-st by ultracentrifugation was used as an allergen extract. Fifty-five out of 487 patients with bronchial asthma (11%) had positive RAST, and BPT was also positive in 23 out of 25 patients showing positive RAST. A good agreement was found between RAST and BPT (69.4%), between skin test and BPT (56.3%)and between RAST and skin test (76.9%), respectively. The RAST value was significantly higher in the positive group of skin test and BPT than in the negative group. Most sera from asthmatic patients allergic to both α-st and house dust were specifically absorbed either α-st or with house dust, indicating that most patients allergic to α-st were independently sensitized to house dust. By contrast, slight cross-reactivity between two allergens was observed only in one case. The results obtained strongly suggest that α-st might play a significant role in asthma attack as a specific allergen.View full abstractDownload PDF (993K) -
Masamichi Tazawa, Akihiro MorikawaArticle type: Article
1985 Volume 34 Issue 6 Pages 379-386
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSSerum IgG antibodies to mites (Dermatophagoides farinae) in patients with asthma and in healthy children were studied using enzyme-linked immunosorbent assay (ELISA). The following results were obtained. 1) IgG antibodies to mites were estimated to increase with age even in healthy as well as asthmatic children. 2) In patients with bronchial asthma, IgG antibodies to mites were higher than those of healthy children. 3) There was no correlation between the titers of the blocking antibodies to house dust using the double injection method and levels of IgG, IgG4 antibody to mites in asthmatic children.View full abstractDownload PDF (754K) -
Yoshio Takeuchi, Yoko Nishimura, Tatsusuke Yoshikawa, Jun-ichi Kuriyam ...Article type: Article
1985 Volume 34 Issue 6 Pages 387-393
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSShoseiryuto, Chinese blended medicine consisting of eight crude drugs, seems to be an effective drug for the treatment and prevention of allergic disease. However, little information is available on its pharmacological action and clinical effects. The purpose of this paper is to investigate the pharmacological action of shoseiryuto in more detail by comparing experimental results with those obtained by tranilast and ketotifen. The results obtained were as follows. 1. Shoseiryuto (83 mg/kg), tranilast (1.65 mg/kg) and ketotifen (0.015 mg/kg) were orally administrated 2 or 3 hrs before antigen challenge inducing IgE mediated PCA. The results showed that these 3 drugs have a similar suppressing effect on the induction of PCA. 2. Guinea pigs were treated with each compound for 10 days successively and on the day they were passively sensitized with IgE antibody. On day 1 or 3 after discontinuance of the treatment, the challenging antigen was injected intravenously, but systemic anaphylactic shock was not elicited in all cases. Also no change of histamine levels in blood was observed compared with the samples before and after eliciting. 3. The suppressing effect of these durgs on histamine, serotonin and acetylcholine inducing inflammatory reactions were compared. Shoseiryuto showed a inhibitory effect on histamine, serotonin and acetylcholine induced inflammatory reactions while tranilast did not inhibit histamine induced reaction and ketotifen did not inhibit acetylcholin and serotonin induced reactions. From these results, it was indicated that the anti-allergic effect of shoseiryuto is about the same as that of the other two drugs, while the pharmacological effect seems to be differ from that of tranilast and ketotifen.View full abstractDownload PDF (921K) -
Masato Mitsuhashi, Hiroshi Tamura, Akihiro Morikawa, Takayoshi Kuroume ...Article type: Article
1985 Volume 34 Issue 6 Pages 394-398
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
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Article type: Appendix
1985 Volume 34 Issue 6 Pages 399-401
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
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Article type: Cover
1985 Volume 34 Issue 6 Pages Cover27-
Published: June 30, 1985
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (194K)
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