Japanese Journal of Allergology
Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884
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Volume 44, Issue 2
Displaying 1-18 of 18 articles from this issue
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  • [title in Japanese]
    Article type: Cover
    1995 Volume 44 Issue 2 Pages Cover13-
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.Cover13
    JOURNAL FREE ACCESS
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  • [title in Japanese]
    Article type: Cover
    1995 Volume 44 Issue 2 Pages Cover14-
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.Cover14
    JOURNAL FREE ACCESS
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  • [title in Japanese]
    Article type: Appendix
    1995 Volume 44 Issue 2 Pages App3-
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.App3
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  • The host defense : Proposal of primitive T cell response (PT response)
    Kikuo Nomoto
    Article type: Article
    1995 Volume 44 Issue 2 Pages 59-63
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.59
    JOURNAL FREE ACCESS
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  • EFFECT OF FOG ON DIURNAL CHANGES IN PEAK EXPIRATORY FLOW RATES IN AN ASTHMATIC
    Hiroshi Tanaka, Shin-ichi Honma, Akihiro Imada, Fumiko Sugaya, Shosaku ...
    Article type: Article
    1995 Volume 44 Issue 2 Pages 64-69
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.64
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    To evaluate the effects of fog on asthmatics, we analyzed the symptoms of a 45-year-old female during the foggy season and the relation between diurnal peak expiratory flow rate (PEFR) and fog and other meteorological factors. Her asthma attacks had been induced by specific smells: perfume, smoke from burning grass or industrial smoke. Two years previously, she had moved to the suburbs of Sapporo, where fog frequently occurs. From that time her asthmatic symptoms had been exacerbated, so it was suspected that the fog might have had some influence. We analyzed 251 measurements of PEFR from June to August 1994. The average and standard deviation of PEFR in the absence of fog and specific smells was 403 ± 40 L/min (n=195). PEFR was significantly lower (p<0.01) when it was foggy (347 ± 60 L/min; n=40), when specific smells were present (333 ± 60 L/min; n=5) and when there were both fog and specific smells (340 ± 53 L/min: n=11). On the other hand, there were no changes associated with other meteorological factors: barometric pressures, relative humidity, mean temperature, minimal temperature and most frequent wind direction. These results suggested that the inhalation of fog decreases PEFR and is an exacerbating factor in bronchial asthma.
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  • INVESTIGATION INTO THE THERAPEUTIC EFFICACY OF CONTINUOUS ISOPROTERENOL INHALATION IN RELATION TO RESPIRATORY INFECTIONS IN ASTHMATIC CHILDREN
    Hiroyuki Uchiyama, Toshihiko Obata, Toshikazu Tsubaki, Naoya Sakaguchi ...
    Article type: Article
    1995 Volume 44 Issue 2 Pages 70-76
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.70
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    In our Department, continuous isoproterenol inhalation therapy has been conducted on status asthmatics over the last 10 years. In the present study, we investigated whether there are any differences in the therapeutic efficacy of continuous inhalation of isoproterenol in the presence or absence of respiratory infections which may induce or aggravate asthma attacks. The treatment period was significantly longer in patients with pneumonia. Further prolongation of the treatment period was noted in patients with atelectasis. However, there were no apparent differences in therapeutic efficacy according to age or the severity of attacks. These findings suggest that continuous inhalation of isoproterenol is very effective for status asthmatics if respiratory infections are thoroughly controlled.
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  • IgE PRODUCTION AND GENE EXPRESSION OF INTERLEUKIN-4 AND INTERFERON-γ BY PERIPHERAL MONONUCLEAR CELLS IN ASTHMATIC CHILDREN
    Tokuko Mukoyama, Kunio Ichikawa, Minoru Baba, Takeshi Noma
    Article type: Article
    1995 Volume 44 Issue 2 Pages 77-85
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.77
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    In asthmatic children without he egg allergy, spontaneous IgE production of PBMC showed 1.27 ± 0.28 IU/ml (Mean ± SE) and IgE production of Dermatophagoides farinae (Df) stimulated PBMC after which IFN-γ decreased to 0.89 ± 0.23 IU/ml (Mean ± SE) (p<0.001). IgE production of Ovalbumin (OVA) stimulated PBMC after which IFN-γ showed no decrease. In asthmatic children with hen egg allergy, IgE production of OVA stimulated PBMC and IFN-γ decreased to 1.0 ± 0.52 IU/ml (Mean ± SE). In spontaneous IgE production it was 1.61 ± 0.91 IU/ml. (p<0.05). IL-4mRNA was expressed in spontaneous PBMC in asthmatic children, but not in healthy non atopic children. The expression of IL-4 mRNA was suppressed in Df stimulated PBMC followed by IFN-7 in as thmatic children. In asthmatic children, IFN-γ mRNA were expressed in Df stimulated PBMC after which IFN-γ. And simultaneously IgE production in Df stimulated PBMC were suppressed by addition of IFN-γ.
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  • AM EPIDEMIOLOGICAL STUDY OF FACTORS RELATING TO MERCURY SENSITIZATION
    Kazuhiro Sato, Yukinori Kusaka, Makoto Yanagihara, Keiichi Ueda, Tomio ...
    Article type: Article
    1995 Volume 44 Issue 2 Pages 86-92
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.86
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    We investigated factors relating to mercury sensitization in 156 medical students (mean age 22.7 ± 2.4, mean ± S.D., male 113, female 43). Their allergic symptoms, lifestyles and family histories were studied by questionnaire. Patch tests were performed on them with HgCl_2 (0.05%aq.), NiSO_4 (5%aq.), PPD (2%pet.) and urushiol (0.01%pet.). Anti-dermatophagoides and anti-cryptomeria pollen IgE antibodies in serum were also measured. While the positive rates of urushiol, nickel and PPD were 11.1%, 5.1% and 2.6%, respectively, that of mercury was as high as 12.8%. Each allergen specific antibody positivity and past histories of allergic diseases were not associated with mercury sensitization (by the chi-square test). Mercury sensitized students had significantly more frequently experienced eczema caused by cosmetics, shampoos, soaps and haircreams (by the chi-square test, p<0.005). They also had significantly more teeth treated with metals compared to the controls (one-tailed t-test, p<0.05). And their urinary mercury concentrations were significantly higher than those of the controls (one-tailed t-test, p<0.05). These findings suggest that mercury sensitization is associated with exposure to mercury in the living environment.
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  • Clinical Effect of Nd : YAG Laser Treatment on the Allergic Rhinitis
    Hirotaka Ito, Motohiko Suzuki, Shinichiro Mamiya, Shunji Kitao, Itsupe ...
    Article type: Article
    1995 Volume 44 Issue 2 Pages 93-95
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.93
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  • A case of agranulocytosis which occurred several hours after the readministration of D-penicillamine accompanied by shivering-chillness
    Masao Negishi, Asako Matsuda, Shuji Kaga, Hirohito Kanemitsu, Mikio Ha ...
    Article type: Article
    1995 Volume 44 Issue 2 Pages 96-99
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.96
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  • EFFECT OF DEXAMETHASONE ON INTERCELLULAR ADHESION MOLECULE-1 EXPRESSION ON CULTURED BRONCHIAL EPITHELIAL CELLS STIMULATED BY INFLAMMATORY CYTOKINES
    Masako Yasuda, Fumio Kokubu, Hiroyuki Izumi, Satoshi Matsukura, Hisahi ...
    Article type: Article
    1995 Volume 44 Issue 2 Pages 100-103
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.100
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    Bronchial asthma is characterized as a chronic inflammation of the airway that causes an infiltration of lymphocytes and eosinophils. Cell to cell interaction or cell to tissue interaction is essential for infiltration of eosinophils to underlying tissues. These phenomena are closely related to the expression of intercellular adhesion molecule-1 (ICAM-1). Inhalation of steroids, such as beclomethasone dipropionate, is commonly used to cure airway inflammation. In this study, we investigated the effect of cytokines on ICAM-1 expression on human bronchial epithelial cell lines, NCI-H_<292>. Moreover, the effect of dexamethasone on ICAM-1 expression stimulated by IL-1β, TNF-α and IFN-γ was observed. Treatment with IL-1β, TNF-α and IFN-γ dose-dependently increased ICAM-1 expression on NCI-H_<292> cells. Inhibitory effects were exerted by dexamethasone on ICAM-1 expression in cells stimulated by IL-1β and IFN-γ in a dose-dependent manner, but not in cells stimulated by TNF-α. These results suggest that the inhibition of ICAM-1 expression could be related to the pharmacological action of steroid drugs.
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  • [title in Japanese]
    Article type: Appendix
    1995 Volume 44 Issue 2 Pages 105-
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.105_1
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  • [title in Japanese]
    Article type: Appendix
    1995 Volume 44 Issue 2 Pages 105-
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.105_2
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  • [title in Japanese]
    Article type: Appendix
    1995 Volume 44 Issue 2 Pages 106-
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.106_1
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  • [title in Japanese]
    Article type: Appendix
    1995 Volume 44 Issue 2 Pages 106-
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.106_2
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  • [title in Japanese]
    Article type: Appendix
    1995 Volume 44 Issue 2 Pages 106-
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.106_3
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  • [title in Japanese]
    Article type: Appendix
    1995 Volume 44 Issue 2 Pages 107-110
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.107
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  • [title in Japanese]
    Article type: Cover
    1995 Volume 44 Issue 2 Pages Cover15-
    Published: February 28, 1995
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.44.Cover15
    JOURNAL FREE ACCESS
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