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Volume 47, Issue 7
Displaying 1-14 of 14 articles from this issue
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Article type: Cover
1998 Volume 47 Issue 7 Pages Cover20-
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (52K) -
Shigeto Kawashima, Yuichi Takahashi, Norio SahashiArticle type: Article
1998 Volume 47 Issue 7 Pages 649-657
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSIt is important to forecast the beginning day of Japanese cedar pollen release for taking the preventive medical measure. We analyzed the relation between the beginning day of pollen release and the changing pattern of daily air temperature. A simple and practical method for forecasting the beginning day of pollen release is suggested. Polynomial of degree three was applied to represent the general variation pattern of air temperature. Multiple correlation coefficients between parameters of the polynomial and the beginning days of pollen release were 0.88 for the difference by year, and 0.81 for the difference by place. It was shown that the minimum value and the date of the fitted polynomial curve were related closely to the difference in the beginning day of pollen release by year. The minimum value and the date of the original series of air temperature showed high correlation with the difference in the beginning day of pollen release by place. We propose to use the minimum value and the date of original series and fitted curve of air temperature for forecasting the beginning day of cedar pollen release.View full abstractDownload PDF (918K) -
Yasuo Arai, Yasuyuki Sano, Koji Ito, Eisaku Iwasaki, Tokuko Mukouyama, ...Article type: Article
1998 Volume 47 Issue 7 Pages 658-666
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSObjects The airm of this study was to investigate in adult asthmatics, which kinds of food allergen can cause a positive reaction by skin scratch test and cause symptoms when administered as a food challenge. Subjects and method Three thousand one hundred and two adult asthmatic patients were submitted to skin scratch tests with housedust mite. Japanese cedar extracts and 33 types of food. Sixty one adult asthmatic patients with a history of immediate, adverse reactions after food ingestion underwent open food challenge. Result Six hundred and twenty five of 3102 subjects (20.1%) had a positive test to one or more food allergens. The commonest food allergens were shrimp (27.7%), crab (27.7%), yeast (23.8%) and buckwheat (15.8%). The positive tests of shrimp, egg and cow's milk were highest in patients under 20 years and decreased with age, however the test rates of crab and soybean were not influenced by age. Positive food challenge responses occurred in 30/60 subjects (50%). The foods, which most of ten provoked a reaction, were buckwheat, shrimp, crab and bread. Conclusion Skin scratch test results in adult asthmatics were different from those in atopic children where the commonest foods with positive tests were egg, cow's milk and soybean. Except for patients with a previous life-threatening reaction. Food allergy should be diagnosed by food challenge where a patient's history of adverse reaction to food, positive skin test and RAST strongly support specific food reactivity.View full abstractDownload PDF (667K) -
Saori Kamesaki, Yutaka Suehiro, Keisuke Shinomiya, Hiroshi Matsushima, ...Article type: Article
1998 Volume 47 Issue 7 Pages 667-673
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSLittle is known about the signfiicance of C. pneumoniae in wheezing state in children. In this study, a total of 33 children with exacerbation of bronchial asthma were serologically and bacteriologically analyzed to investigate whether C. pneumoniae infection is associated with wheezing in children with bronchial asthma. 1) Of the 33 patiens, 12 (39%) had an acute antibody rise against C. pneumoniae. C. pneumoniae was isolated from 8 patients (24%) by culture. Based on these findings, 15 cases (45%) were diagnosed as C. pneumoniae infection. 2) There were no significant difference in clinical signs, symptoms and laboratory studies between with and without C. pneumoniae infection. The high incidence of C. pneumoniae infection in children with exacerbation of bronchial asthma suggests its significance as a cause of wheezing. Although there was no specific symptom in C. pneumoniae infection, this infection should be suspected in wheezing children for diagnosis and proper treatment.View full abstractDownload PDF (720K) -
Maki Hasegawa, Eizaburou Nobutani, Naohiro Kaneko, Makoto Kudoh, Shige ...Article type: Article
1998 Volume 47 Issue 7 Pages 674-678
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSTheophylline is widely used for treating patients with bronchial asthma. However, since the therapeutic concentration range is narrow, adverse reactions are frequent and often difficult to control, making monitoring of theophylline concentration mandatory for its efficient and safe use. In this study, we employed the AccMeter^【○!R】 which allowed us measure theophylline concentrations quickly and with ease, and compared it with EIA method. AccMeter^【○!R】 is a kit which consists of two parts. One part consists of a chromatopaper with antitheophylline mouse monoclonal antibody fixed on it, on which a smaple is applied with enzyme-linked theophylline. The other part consists of a coloring solution. We used a part of arterial blood samples collected for gas analysis as trial samples. Both whole blood and plasma from 50 patients who did or did not receive theophlline were analysed. Plasma portions were also used for measurements by the EIA method. Results from all three measurements were almost identical, and showed good correlation. The time necessary for measurement using AccMeter^【○!R】 was about 20 minutes. We consider this method to be useful for clinics due to its simplicity and ease of handling, and the accuracy of the results obtained.View full abstractDownload PDF (506K) -
Hidetoshi Kawahara, Naoya Sakaguchi, Yoji Iikura, Hirohisa Saito, Akir ...Article type: Article
1998 Volume 47 Issue 7 Pages 679-686
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSThirty asthmatic children were examined allergic reaction against egg white, gelatin and vaccine solution before and after vaccination using skin prick test. We also measured the levels of specific IgE and IgG antibody against gelatin. The changes in clinical symptoms before and after vaccination were investigated in 25 asthmatic children by evaluating symptom and treatment score. The results were as follows ; (1) In one subject who had delayed type of skin reaction to gelatin, the adverse reaction was also recognized at the skin site around 24 hrs after vaccination. In this subject, the levels of serum specific IgE and IgG to gelatin became positive after 5 months. (2) Specific IgE antibodies to gelatin were not detected in all subjects before and after vaccination. (3) The mean values of asthma symptom score before and after vaccination were 3.3±4.2 and 1.5±3.3 respectively. Those of treatment score before and after vaccination were 75.6±35.2 and 76.0±35.0 respectively. These results suggest that skin testing with gelatin and vaccine solution is useful as a screeing method for predicting adverse reactions in asthmatic children and that influenza vaccination can be performed safely in skin test negative children.View full abstractDownload PDF (722K) -
Kazue Yamada, Atsuo Urisu, Yutaka Morita, Hitoshi Ando, Eiko Wada, Shi ...Article type: Article
1998 Volume 47 Issue 7 Pages 687-693
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSOne hundred and ninety one subjects showing histories of immediate hypersensitive response to egg white ingestion and/or positive IgE antibody titers specific for egg white were enrolled in double-blind placebo-controlled oral challenge with freeze and dried, heated or heated and ovomucoid-depleted egg white antigens. Seventy seven were male and 114 femal, and their ages ranged from 11 month to 10 years 5 month ; 118 of them had atopic dermatitis, seven had asthma and 33 had both atopic dermatitis and bronchial asthma and 33 had urticaria. One hundred four children developed 147 positive symptoms including 131 immediate reactions and 16 non-immediate reactions by oral challenge tests. Respiratory symptoms were observed in 25 cases (17%) including cough alone in 12 cases (8.2%), and both wheezing and cough in 13 cases (8.8%). These were all observed as immediate reactions and accompanied with dermal symptoms. Frequency of respiratory symptoms correlated with specific IgE antibody titers for egg white. Heated and ovomucoid-depleted egg white was more hypoallergenic than heated or freeze and dried egg white with respect to respiratory symptoms as well as other symptoms. We concluded that respiratory symptoms were provoked through oral challenges with egg white in a part of egg-allergic children.View full abstractDownload PDF (765K) -
Katsuya Fujimori, Eiichi Suzuki, Masaaki ArakawaArticle type: Article
1998 Volume 47 Issue 7 Pages 694-697
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
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[in Japanese]Article type: Article
1998 Volume 47 Issue 7 Pages 698-704
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
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Article type: Appendix
1998 Volume 47 Issue 7 Pages 705-
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
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Article type: Appendix
1998 Volume 47 Issue 7 Pages 706-
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
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Article type: Appendix
1998 Volume 47 Issue 7 Pages 707-708
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (133K) -
Article type: Appendix
1998 Volume 47 Issue 7 Pages 709-712
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (281K) -
Article type: Cover
1998 Volume 47 Issue 7 Pages 713-
Published: July 30, 1998
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (368K)
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