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Volume 49, Issue 11
Displaying 1-19 of 19 articles from this issue
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Article type: Cover
2000 Volume 49 Issue 11 Pages Cover4-
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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Article type: Cover
2000 Volume 49 Issue 11 Pages Cover5-
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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Article type: Appendix
2000 Volume 49 Issue 11 Pages App3-
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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Minoru OkadaArticle type: Article
2000 Volume 49 Issue 11 Pages 1057-1059
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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Koji YamadaArticle type: Article
2000 Volume 49 Issue 11 Pages 1060-1062
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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Kenshi FurushoArticle type: Article
2000 Volume 49 Issue 11 Pages 1063-1065
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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Susumu Harada, Tatsuya Horikawa, Masamitsu IcihashiArticle type: Article
2000 Volume 49 Issue 11 Pages 1066-1073
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSWe surveyed and analyzed cases of food-dependent exercise-induced anaphylaxis(FDEIA)in the Japanese literature. We found 167 cases which were reported as FDEIA since 1983. Analyzing these cases, following characteristic features were revealed: 1)Recent upward trend in the number of reports of FDEIA was noted. 2)Male cases were more frequent than female cases, while about half of the cases were teenager. 3)More than half of the cases were proved to be induced by wheat followed by shrimp. In those under 20, shrimp was the most popular cause rather than wheat. 4)Skin test and/or IgE RAST showed positive results in most cases, suggesting that the response itself is linked to type I allergic reaction. 5)About 40% of the patients had history of atopic disease, indicating that atopic condition may play some role in FDEIA. 6)All cases who performed provocation test with aspirin responded to food challenge and/or exercise in combination with aspirin. This indicates that aspirin plays a key provoking factor in FDEIA. 7)In 17 cases FDEIA attacks were observed during noon recess or physical education class after lunch at school. We stress here the importance of a nation-wide education to school teachers the potential danger of this disorder.View full abstractDownload PDF (921K) -
Takao Shida, Kazuo Akiyama, Maki Hasegawa, Yuuji Maeda, Masami Taniguc ...Article type: Article
2000 Volume 49 Issue 11 Pages 1074-1086
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSFive-year changes in the percentage of positive intradermal test to allergens in patients with bronchial asthma(BA)and allergic rhinitis(AR)over a period of 30 years from 1969 to 1998 were analyzed, with consideration of their association with the yearly changes in the levels of airborne pollens and molds over 30 years. Allergens used throughout the period were house dust, pollens from various plants(Japanese cedar, pine, oak, Japanese alder, Zelkova, orchard grass, ragweed, mugwort and Japanese hop)and molds(Altemaria, cladosporium, Aspergillus, Penicillium and Candida). Overall percentages to house dust were higher in BA patients than in AR patients, but those to pollens were distinctly higher in the latter. Those to molds were higher in BA patients, except that those to Alternaria were about the same in both BA and AR patients. Therefore, the clinical expression of allergy may differ according to the type of allergen to which subjects are sensitized. Over the course of 30 years, the increase in the percentage of positive intradermal test to all of the allergens used was noted in both BA and AR patients, although this did not always reflect the aeroallergen load. This includes the two extremes to pollens from Japanese cedar and pine, either of which is the most common source of allergen in Japan. Significant increases in the percentages to Japanese cedar pollen(from 12.5% to 54.4% in BA patients, and from 35.1% to 81.5% in AR patients)appeared to be roughly correlated to marked increases in pollen count. In contrast, that to pine pollen was kept low at about 2%, because of their weak allergenicity, but abruptly increased to 5-6% in the last decade, despite the almost invariable pollen count over the last 30 years. Therefore, the increased sensitivity to aeroallergens may also be associated with other factors besides their load in the air.View full abstractDownload PDF (1291K) -
Kazuyo KuzumeArticle type: Article
2000 Volume 49 Issue 11 Pages 1087-1092
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSFrom Jun 1996 to May 1999, 1280 infants were examined by the auther 6 times from birth to 12 month-old in each 0, 1, 3, 6, 9, 12 month-old time at NTT Nishinihon Matuyama Hospital. The 12-month cumulative prevalence of AD was 28.5%. Out of the cases 82.2% showed the symptoms before 3 month-old. There were 217 male infants in AD group(59.5%). This percentage was significantly higher than 45.2% in non-AD group(p<0.001). Approximately 700% cases in AD group had family history of allergic diseases. This ratio was significantly higher compared to 49.6% in non-AD group (p<0.001). According to the season of birth, there were significant differences in the 12-month cumulative prevalence of AD (p<0.005). Infants born in the spring, summer, autumn and winter showed 21.1%, 27.2%, 31.3%, and 33.9% of cumulative prevalence of AD respectively. The prevalence of AD at 3 month-old and the ratio that the symptoms appeared before 3 month-old also had similarly significant tendency(p<0.001)(Infants born in the spring showed 15.4% and 73%. Infants born in the winter showed 31.5% and 92.90%). There were no relationship between the cumulative prevalence of AD and the precipitation.View full abstractDownload PDF (689K) -
Nobuo Ishigaki, Chika Masuhara, Kimiko Sakamaki, Yasuko Ishikawa, Kyur ...Article type: Article
2000 Volume 49 Issue 11 Pages 1093-1103
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSSerum eosinophil cationic protein(sECP)levels were measured in 339 patients with childhood asthma, and the clinical courses of these patients were followed for 57 weeks. While considering the history and characteristics of each patient, we examined the correlation between asthma attack frequency and sECP, blood eosinophil count, and serum total IgE(tIgE)to determine their usefulness in predicting asthma attacks. Among patients with no other allergic diseases, sECP levels in patients who had no asthma attacks two weeks before or after the measurement were significantly lower than those of patients who had attacks during the same four-week period. Among patients who had attacks, those patients with no attack for a year after the measurement were also found to have low sECP levels. Similarly, even among patients with asthma attacks and high sECP levels, there were cases where attacks were well controlled using nebulizer treatments with DSCG or BDP. The incident rate of attacks for patients with other allergic diseases and a low sECP was low. Yet there was no common trend in patients with high sECP levels. Moreover, this study detected a significant correlation between sECP level and blood eosinophil count as well as between sECP level and serum tIgE. The most significant correlation with asthma attack frequency was sECP level. Thus, sECP level seems to reflect the allergy activity level, especially two weeks prior to and after the measurement. For patients without other allergic diseases, asthma attack prediction during the two weeks period after the measurement of sECP also seems possible. Therefore, periodic measurement of sECP level is useful in objectively monitoring the improvement of symptoms and establishing the treatment plan, including treatment with DSCG or BDP.View full abstractDownload PDF (1065K) -
Hiroto Usui, Yasuhei Odajima, Yasuhito Yamamoto, Tatsuya Shimizu, Fuji ...Article type: Article
2000 Volume 49 Issue 11 Pages 1104-1107
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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Yumi Yamada, Shigemi Yoshihara, Toshio Abe, Norimasa Fukuda, Makoto Wa ...Article type: Article
2000 Volume 49 Issue 11 Pages 1108-1110
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSRecently, it has been recognized that airway inflammation is the most important pathogenesis of bronchial asthma, and inhaled corticosteroids therapy is effective for childhood asthma. However, using metered dose inhalers(MDI)of beclomethasone dipropionate(BDP)is difficult for infants. In this study, we administered BDP inhalation therapy with a new spacer. Babyhaler, for five cases of early childhood with severe infantile asthma that we could not control even by combination of theophylline round the clock(RTC)therapy and disodium cromoglycate(DSCG)+ β2 Stimulant(β2)regular use. We compared symptom score of asthma attack between the pre-treatment period(prior 2 weeks)and post-treatment period(following 8 weeks)of BDP inhalation therapy with Babyhaler. As a result, symptom score decreased significantly within 4 weeks after treatment of BDP with Babyhaler as compared with the score before treatment of BDP. These findings suggest that Babyhaler is useful for BDP inhalation therapy in infantile asthma.View full abstractDownload PDF (370K) -
Daisuke Hasegawa, Hisashi Kawashima, Shingo Oana, Mayuko Motobe, Michi ...Article type: Article
2000 Volume 49 Issue 11 Pages 1111-1114
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSCasein a component of milk is used for food additives, industrial materials and drugs. However casein is known to be a main allergen in milk allergy. Recently several cases of anaphylaxis to antibiotics including casein have been reported. In this study we investigated casein allergy in milk allergy. 6 out of 8 patients who were positive for milk RAST were also positive for casein RAST. In these positive cases only 3 out of 6 patients had some allergic symptoms after taking antibiotics. In 3 patients DLST was also positive to casein. There was one patient who was positive in DLST without any symptoms after taking the same antibiotics. It is needed to pay attention to casein allergy when giving the medication which includes casein.View full abstractDownload PDF (445K) -
Article type: Appendix
2000 Volume 49 Issue 11 Pages 1115-
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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Article type: Appendix
2000 Volume 49 Issue 11 Pages 1116-1117
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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Article type: Appendix
2000 Volume 49 Issue 11 Pages 1118-1119
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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Article type: Appendix
2000 Volume 49 Issue 11 Pages 1120-1123
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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Article type: Appendix
2000 Volume 49 Issue 11 Pages 1124-1128
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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Article type: Cover
2000 Volume 49 Issue 11 Pages Cover6-
Published: November 30, 2000
Released on J-STAGE: February 10, 2017
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