Japanese Journal of Allergology

Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884

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Volume 53, Issue 5

Displaying 1-39 of 39 articles from this issue

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[title in Japanese]

Article type: Cover
2004 Volume 53 Issue 5 Pages Cover15-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.Cover15

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[title in Japanese]

Article type: Cover
2004 Volume 53 Issue 5 Pages Cover16-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.Cover16

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REEVALUATION OF HYGIENE THEORY

Tadao Enomoto

Article type: Article
2004 Volume 53 Issue 5 Pages 465-468
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.465

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TOLL-LIKE RECEPTOR AND ALLERGY

Hiroko Ushio

Article type: Article
2004 Volume 53 Issue 5 Pages 469-475
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.469

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DEATH FROM ASTHMA ATTACKS IN TOHOKU DISTRICT : Results from Questionnaire Surveyed from 1992 to 2001

Gen Tamura

Article type: Article
2004 Volume 53 Issue 5 Pages 476-483
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.476

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In Tohoku district, death from asthma attacks was surveyed from 1992 to 2001. After presence of death from asthma attacks during the previous year were confirmed by postcard at the beginning of every February, details of each case were asked by questionnaire. In total, 299 cases (male : 186, female : 113) were recognized as death from asthma attacks. Middle-aged and older asthmatics over 50 year accounted for 2/3 of the cases and the most death was recorded in asthmatics in the second decade of life under 50. Out-patients accounted for 78%. When they visited hospitals, 60% was in cardio-pulmonary arrest and 89% was in more critical condition than severe attacks. About duration of attacks from the onset to their death, within 2 hrs accounted for 25.6%, within Iday did for 39.6%, and over Iday did for 34.8%. Although the most death was found in patients whose duration of asthma was between 1 and 10 years, 16 cases died within 1 year from the onset of their asthma. About severity during the past year, 34% had severe asthma, 45% moderate, and 21% mild. Number of death from asthma attacks in Tohoku district was clearly reduced over the past 5 years. The number was reduced to about one-fourth of that at the beginning of survey.

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EPIDEMIOLOGIC STUDY ON THE PREVALENCE OF THE SICK HOUSE SYNDROME IN JAPAN

Yuko Koyasu, Naho Sakai, Takanori Imai, Akira Kanda, Takeshi Kawaguchi ...

Article type: Article
2004 Volume 53 Issue 5 Pages 484-493
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.484

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[Purpose] Sick house syndrome (SHS;sick house syndrome) presents healthy damage owing to the indoor environment of a building. Although SHS is recognized socially, there is no medical definition and its illness concept is also ambiguous. This time, large-scale epidemiology investigation about SHS of our country was conducted. [Method] The investigation paper in the "epidemiological research on SHS" group of the Ministry of Health, Labour and Welfare was used. The reply of 8737 adults and 9387 children was obtained. [Result] By the definition of a disease, prevalence of SHS was 8.5 to 22.1% at the adult and 5.6-19.8% in the child. Cause environmental substances were "a shampoo, makeup and a perfume", "the smell of a wall or the building materials of a floor", and"paint". There was no significant difference in SHS development of symptoms in construction years and the situation of extension and alteration of a dwelling. As a feature of a life style, symptoms developed in the strong group of stress and sensitive to a smell developed mostly. [Consideration] Prevalence differed greatly by how SHS is defined. In order to diagnose truer SHS, we think that the prudent definition based also on the international standard is required.

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RICE POLLEN ASTHMA AND POLLINOSIS IN CHILDHOOD : SEASONAL ASTHMA AND ALLERGIC RHINOCONJUNCTIVITIS DURING THE PERIOD OF RICE POLLEN EMISSION IN THE SURROUDING AREA OF RICE FIELD

Akihiko Yabuhara, Keiko Shimojima, Megumi Hokura, Takehiko Ishida, Hir ...

Article type: Article
2004 Volume 53 Issue 5 Pages 494-501
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.494

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Although in 1969, rice pollen was first reported as a cause of asthma, rice pollen allergy has not been studied after the first report and thus the allergic significance of rice pollen is not well recognized at present. We investigated the sensitization to various allergens and the residential areas in children with the symptoms of asthma or rhinoconjunctivitis during the first decade of August, and measured rice pollen-specific IgE antibodies. Eighty-eight children (57 boys and 31 girls, mean age 8.5 ± 2.9 years) with bronchial asthma or allergic rhinitis/conjunctivitis were included in this study and divided into two groups : children with (n = 21) or without (n = 67) symptoms during this period. The positivity rate to orchard grass pollen and the rate of residence in the surrounding area of rice field were high (81%, P = 0.008 and 86%, P <0.001, respectively) in children with allergic symptoms, as compared to the values (48%and 27%, respectively) in children without symptoms. As the rice pollen season in Nagano occurs in the first decade of August, we measured rice pollen-specific IgE antibodies in 8 patients with symptoms during this period I all of these patients showed positive IgE antibodies to rice pollen. The RAST-inhibition assay using orchard grass and rice pollen indicated cross-allergenecity between these two pollen and also the existence of rice pollen-specific allergens. These results suggest that rice pollen induces seasonal asthma and allergic rhinoconjunctivitis during the first decade of August, which is the rice pollen season, in the surrounding area of rice fields.

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COMPARISON OF THE BRONCHODILATOR EFFECT OF SALBUTAMOL BETWEEN PRESSURE METERED DOSED INHALER AND DRY POWDER INHALER IN PATIENTS WITH STABLE BRONCHIAL ASTHMA

Yuzo Yoshimi, Masaki Fujimura, Masahide Yasui, Kazuo Kasahara, Shinji ...

Article type: Article
2004 Volume 53 Issue 5 Pages 502-507
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.502

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Recently, dry powder inhaler (DPI) was more available than pressure metered dosed inhaler (pMDI) for the inhalation therapy of the respiratory disease. But there are differences in the lung deposition of the drug in these devices. We investigated the bronchodilator effect of salbutamol inhalation with two device, pMDI and Tubuhaler on the stable 8 asthmatic patients. The time course of FEV_1 had a no significant difference between two devices. ΔAUC (= difference between area under the curve for time course of increase in FEV_1 via pMDI and via DPI) and Δmax FEV_1 (= difference between maximum increases in FEV_1 following inhalation of salbutamol via pMDI and DPI) were defined as the index of difference of bronchodilator effect between the two devices. PMDI was more effective on improving the pulmonary function in subjects with severely decreased FEV_1 and FEV_<1%> than DPI. These results may reflect the correlation of inspiratory flow rate and drug deposition. PMDI is still useful on the part of asthmatic patients with decreased pulmonary function.

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SYMPTOMS IN ASTHMATICS LIVING IN COLD DISTRICTS DURING WINTER

Shinobu Osanai, Toru Takahashi, Toshiyuki Ogasa, Hitoshi Nakano, Yoshi ...

Article type: Article
2004 Volume 53 Issue 5 Pages 508-514
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.508

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Exposure to cold is known as a potential exacerbating factor in asthmatics. However, few studies have investigated severity of symptoms during daily life in winter for asthmatics living in northern Hokkaido, the coldest region in Japan. We sent questionnaires to 126 asthmatics living in northern Hokkaido, and obtained answers from 116 patients (52 males, 64 females). Breathing difficulties during cold-air exposure were reported by 62.1% of patients. Furthermore, 19.6% of patients had experienced the need for bronchodilators following cold-air-induced attacks. Limitations to daily life in winter caused by exacerbated asthmatic symptoms were recognized by 48.3% of patients. Asthmatic exacerbation was experienced by 30% of patients in summer (May to August) , compared to>35% in winter (September to April). No significant differences in results were noted between atopic and non-atopic patients. Improvements in respiratory symptoms during winter are thus necessary for better quality of life in asthmatics living in cold districts.

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ANALALYSIS OF FACIAL LESIONS ON ADULT TYPE ATOPIC DERMATITIS WITH ANTI-FUNGUS DRUG (TERBINAFINE HYDROCHLORIDE) : ANALYSIS OF SERUM ANTI-MALASSEZIA IgE ANTIBODY TITERS AND HISTAMINE RELEASE TEST

Hideki Maejima, Chiharu Tokunaga, Satoshi Kaneko, Hideki Mukai, Akio A ...

Article type: Article
2004 Volume 53 Issue 5 Pages 515-521
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.515

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Malasseziafurfur has been described as an aggravating factor in facial lesions of atopic dermatitis, and oral antifungal agents have been reported to be effective against these lesions. We used terbinafine hydrochloride to treat 15 patients with adult-type atopic dermatitis and evaluated its efficacy by measuring the improvement in facial skin manifestations, serum IgE values, and serum anti-Malassezia IgE antibody titers. A histamine release test (HRT) for Malassezia. was also performed in 6 of the 15 patients. The facial skin manifestations improved in 8 (53.3%) of the 15 patients, and there were significant simultaneous decreases in their serum IgE values. The serum anti-Malassezia IgE antibody titer decreased significantly in all 15 patients. However, no significant correlation was observed between the HRT and the facial skin manifestations. We concluded that oral terbinafine hydrochloride is effective against the facial lesions of atopic dermatitis patients and this is possibly caused by decrease of Malassezia antigen in the facial lesions.

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[title in Japanese]

[in Japanese]

Article type: Article
2004 Volume 53 Issue 5 Pages 522-523
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.522

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 523-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.523

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 524-526
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.524

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 527-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.527_1

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 527-528
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.527_2

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 529-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.529

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 530-533
Published: May 30, 2004
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DOIhttps://doi.org/10.15036/arerugi.53.530

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 534-535
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.534

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 536-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.536_1

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 536-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.536_2

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 536-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.536_3

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 537-538
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.537

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 539-541
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.539

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 542-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.542

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 543-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.543_1

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 543-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.543_2

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 544-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.544

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 545-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.545

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 546-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.546_1

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 546-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.546_2

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 547-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.547

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 548-549
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.548

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 550-551
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.550

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 552-553
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.552

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 554-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.554

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 555-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.555

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 556-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.556_1

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 5 Pages 556-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.556_2

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[title in Japanese]

Article type: Cover
2004 Volume 53 Issue 5 Pages Cover17-
Published: May 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.Cover17

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