-
Article type: Cover
2005 Volume 54 Issue 5 Pages
Cover16-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Index
2005 Volume 54 Issue 5 Pages
Toc6-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Hachiro Tagami
Article type: Article
2005 Volume 54 Issue 5 Pages
445-450
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Hidekuni Inadera
Article type: Article
2005 Volume 54 Issue 5 Pages
451-454
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Takayuki Fukuzumi, Eijiro Kobayashi, Toshiyuki Aoki, Yasunori Sasai, S ...
Article type: Article
2005 Volume 54 Issue 5 Pages
455-463
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
Background : This is probably the first report of a population study on infantile eczema performed for 12 months at two ages of 4 months and 10 months on the same infant group. Methods : The Fujiidera Health Center services the health needs of 181,994 inhabitants of Habikino and Fujiidera cities. Between September 1990 and August 1991,1775 newborns were called for a health check-up performed twice a months when they reached 4 months of age. This was repeated for a year when the infants reached 10 months of age. A total of 1493 4-month old infants and 1264 10-month old infants were examined. An expert dermatologist joined this and performed a complete skin examination throughout the study. The eczematous skin changes were evaluated at 50 different points on the body and scored using an originally made chart. Scratch marks were also evaluated at each area. Based on the scores computed eczema was diagnosed when the total score crossed a threshold number. Based on this the examiner diagnoses were categorized as follows : Degree 1 : no need to visit a doctor, Degree 2 : visit to doctor required, Degree 3 : treatment required. Gender was not considered. The data was analyzed by an originally made software using DEC-7000 computer. Results : Of all the 4-month old Infants examined 329 (22.0%) were initially diagnosed to have eczema while of all the 10-month old infants examined 268 (21.2%) were initially diagnosed to have eczema. Further, out of the 329 4-month old infants initially diagnosed with eczema, 228 were again examined when they were 10-months old. Of this sample ; 123 (9.7%) infants showed continued symptoms of eczema and 165 (13.1%) infants no longer showed signs of eczema. In addition, out of the 976 4-month old infants initially diagnosed without eczema. 145 (11.5%) newly developed eczema at 10 months. Hence the cumulative diagnosis rate of eczema reached 34.3%. Meanwhile the monthly diagnosis number was significantly higher in Feb (OR 1.84, p=0.031) and significantly lower in Aug (OR 0.21, p<0.001) than the expected number calculated from monthly examination number and the annual diagnosis rate at 4 months. This observation was also the case at 10 months (Feb ; OR 2.19, p=0.02, Aug ; OR 0.36, p=0.015) . The degree of eczema was significantly higher (p<0.001. Mann-Whitney ' s U test) at 4 months than 10 months. When this was seen monthly, degree 3 was most prevalent in February-March, while degree 2 was most prevalent in October-January for the 4-month olds. For the 10-month olds, both the degree 3 and degree 2 were quite low throughout the year and only degree 1 showed a monthly change similar to degree 2 plus degree 3 of the 4-month olds. Conclusion : We therefore conclude that eczematous skin manifestations of infantile eczema are easily changeable by age at less than 1 year and are strongly influenced by seasons.
View full abstract
-
Nanae Ikeda, Aya Monden, Satoshi Ogino
Article type: Article
2005 Volume 54 Issue 5 Pages
464-470
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
Background : Recently the number of patient with Japanese cedar pollinosis is increasing. We think many patients are not consulted by a doctor, therefore the questionnaire survey only at hospitals is not enough to know patient's trend. In this study, we examined the trend of patients with pollinosis by the use of a web site. Methods : For this examination, questionnaire on web site was used from February 1 to April 30,2003. In this time, the correlation between the pollen counts and access number, how to collect information of pollinosis and the presence of early treatment were focused. Results : The access number to the web site was 348,045 and 1,612 patients answered the questionnaire. There was a good correlation between Japanese cedar pollen counts and the access number to the web site. Most patients (61.2%) collected information about pollinosis and pollen counts by television/radio as well as internet. Patients under 40 years had a medical consultation after the onset symptoms of pollinosis, on the other hand patients over 40 years had a medical consultation before the onset symptoms of pollinosis. Patients who lived in east Japan had a medical consultation before the onset of pollinosis and lived in west Japan after having symptoms. Conclusion : It concluded that age and area of patients influenced the patient's trends. Nowadays the spread of internet is remarkable. Therefore, the reliable presentation of information of pollinosis through internet become more important.
View full abstract
-
Motohiro Ebisawa, Hiroshi Tachimoto, Kaori Ikematsu, Chizuko Sugizaki, ...
Article type: Article
2005 Volume 54 Issue 5 Pages
471-477
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
Background : There is few data to prove the safety of egg shell calcium as allergen. Especially , noncalcinated egg shell calcium is not allowed to use without the description of origin of egg on food labels in Japan. Method : We evaluated the possibly contaminated egg allergens in commercial non-calcinated egg shell calcium made from egg by in vitro methodologies (SDS-PAGE, western blotting, inhibition ELISA and sandwich ELISA) and by single-blind oral non-calcinated egg shell calcium challenge on 6 egg hypersensitivity patients. Resuts : The allergenic activity of non-calcinated egg shell calcium was almost negligible compared to egg white by all in vitro methods. Furthermore, six patients with egg hypersensitivity were unresponsive to oral non-calcinated egg shell calcium challenge test. Conclusion : These results indicate that there is little contamination of egg white in non-calcinated egg shell calcium, and that the allergenic activity of non-calcinated egg shell calcium is equivalent to that of calcinated egg shell calcium.
View full abstract
-
Maki Hasegawa, Mamoru Ohtomo, Haruhisa Mita, Kazuo Akiyama
Article type: Article
2005 Volume 54 Issue 5 Pages
478-484
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
Background : "Sick House Syndrome" is thought to be an illness caused by indoor environments such as allergens, bacteria and chemical compounds. But it is not yet an established clinical entity. "Sick House Syndrome" overlaps in part with Multiple Chemical Sensitivity (MCS) whose symptoms are induced by very small amount of volatile chemical compounds. Methods : We selected possible cases of MCS from patients who visited our specially built facility for " Sick House Syndrome" by tentative criteria as follow. (1)histories of chemical compounds exposure, (2)multi-organ symptoms, (3)exclusion of other disease (s) which may be responsible for symptoms, (4)chronic symptoms. Clinical aspects of the possible cases were examined. Results : Fifty out of about 130 patients were the possible cases of MCS, 38 females and 12 males, aged 15 to 71 years old. Forty two out of 50 patients (84%) had a history and/or a complication of allergic diseases. This rate is much higher than the rate of prevalence of allergic diseases in Japanese population. Allergic rhinitis was the most popular allergic disease in the possible cases. Total lgE values were relatively low, 32 patients (64%) showed the lgE value below 200 IU/'ml. No patients showed anti-formaldehyde lgE antibody. Decreased reactivity and decreased sensitivity of histamine release from peripheral blood were observed after challenge tests with chemical compounds. Conclusion : Allergic reactions can not be the causative mechanism (s) of the MCS, which is induced by multiple and different chemical compounds. Our results, however, suggest that patients having allergic diseases may be easily suffered from MCS or MCS may strengthen symptoms of allergic diseases.
View full abstract
-
[in Japanese]
Article type: Article
2005 Volume 54 Issue 5 Pages
485-486
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese]
Article type: Article
2005 Volume 54 Issue 5 Pages
487-488
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
489-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
490-492
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
492-493
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
493-495
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
496-499
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
500-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
500-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
501-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
501-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
502-504
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
505-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
506-507
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
507-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
508-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
509-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
510-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
511-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
512-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
513-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
513-514
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
514-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
514-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
515-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
516-517
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
518-519
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
520-521
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
522-524
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
525-526
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
526-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
527-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
528-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
529-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
529-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
2005 Volume 54 Issue 5 Pages
529-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Cover
2005 Volume 54 Issue 5 Pages
Cover17-
Published: May 30, 2005
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS