Japanese Journal of Allergology
Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884
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Volume 56, Issue 10
Displaying 1-35 of 35 articles from this issue
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  • [title in Japanese]
    Article type: Cover
    2007 Volume 56 Issue 10 Pages Cover4-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.Cover4
    JOURNAL FREE ACCESS
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  • [title in Japanese]
    Article type: Cover
    2007 Volume 56 Issue 10 Pages Cover5-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.Cover5
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages App2-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.App2
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages App3-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.App3
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages App4-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.App4
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages App5-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.App5
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  • 3. Pathomechanism and Treatment of Severe Cutaneous Drug Reactions(DRUG HYPERSENSITIVITY)
    Zenro Ikezawa
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1231-1239
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1231
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  • ORGAN DAMAGES CAUSED BY DRUG HYPERSENSITIVITY AND THEIR TREATMENT
    Yasunobu Takizawa, Shigeko Inokuma
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1240-1247
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1240
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1248-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1248
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  • CHARACTERIZATION OF ALLERGENS AND ITS CLINICAL APPLICATION
    Hiroshi Yasueda
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1249-1253
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1249
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  • STRANGER & DANGER HYPOTHESIS AND ALLERGIC DISEASE
    Masamoto Kanno
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1254-1261
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1254
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  • INVESTIGATION OF THE VARIATION OF CRY J 2 CONCENTRATION IN POLLEN AMONG SUGI (CRYPTOMERIA JAPONICA D. DON) TREES USING A NEWLY ESTABLISHED EXTRACTION METHOD
    Yoko Fukuda-Goto, Hiroshi Yasueda, Akemi Saito, Teiji Kondo
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1262-1269
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1262
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    Background : Selection of low-allergen trees is under consideration for the reduction of Sugi (Cryptomeria japonica) pollinosis. The extraction method of Cry j 2 was established and then the variation of Cry j 2 concentrations in pollen among Sugi trees was investigated. Methods : The extraction efficiency of Cry j 2 was compared among buffers with different pH, ionic species and NaCl concentration. The Cry j 2 concentration in the pollen of 140 trees was measured using the most efficient buffer. Results : NaHCO_3 (0.125M)+0.5M NaCl buffer showed the highest Cry j 2 extraction efficiency. The mean and standard deviation of Cry j 2 concentration among 140 trees was 404±189μg/g pollen, which was equivalent to that of Cry j 1 (435±169μg). Conclusion : We revealed that the variation of Cry j 2 concentrations was as large as that of Cry j 1 in the pollen among trees using the newly developed extraction method.
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  • A SURVEY OF ATOPIC DERMATITIS AND SKIN BARRIER FUNCTIONS IN JAPANESE AND CHINESE SCHOOL STUDENTS
    Yasuyuki Sumikawa, Yuriko Ueki, Akira Miyoshi, Lei Cheng, Min Yin, Hai ...
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1270-1275
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1270
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    Background : The comparative studies of the prevalence of atopic dermatitis and skin barrier functions in Japanese and Chinese were performed. Methods : Clinical investigations were performed in 68 elementary school students in Lhasa, Tibet Autonomous Region and 67 students in Yixing, Jiangsu Province in China, and 99 students in Nishinomiya, Hyogo in Japan. Transepidermal water loss (TEWL) and capacitance were measured. Questionary survey about bathing frequency was also performed for students in Lhasa, Yixing and Osaka. Result : The prevalence rate of atopic dermatitis was 0% in Lhasa, 2.63% in Yixing, 4.26% in Nishinomiya. TEWL of students in Nishinomiya was higher than that in Yixing and Lhasa. Capacitance of students in Lhasa was lower than that in Nishinomiya and Yixing. The frequency of taking a bath in Lhasa was about 2.2 times per month and fewer than that in Nishinomiya and Yixing. Conclusion : There was tendency that the prevalence of atopic dermatitis increased according to increase of TEWL. It was thought that more investigations are necessary whether the development of habitat and environment influence the prevalence of atopic dermatitis and skin barrier function.
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  • ORAL ALLERGY SYNDROME DUE TO PLANT-DERIVED FOODS : A CLINICAL REVIEW OF 63 PATIENTS OVER A PERIOD OF 6 YEARS
    Naoko Inomata, Akiko Morita, Mio Kirino, Haruna Yamazaki, Jyunko Yamag ...
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1276-1284
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1276
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    Background : The clinical features of many patients with oral allergy syndrome (OAS) due to plant-derived foods have rarely been reported in Japan. Objectives : We aimed to determine the causative foods of OAS due to plant-derived foods based on clinical features and skin prick tests (SPTs). Furthermore, we aimed to elucidate the association between causative foods and sensitized pollens in patients with OAS due to plant-derived foods. Methods : SPTs and specific IgE measurements (CAP-FEIA : CAP) were performed in relation to foods and pollens in 118 patients with positive histories of OAS due to plant-derived foods. Patients with positive histories and with positive skin test responses were identified as having type I allergy to the causative foods. Results : The mean age of 63 patients with positive histories and positive skin test responses was 29.2 years (range, 2-61 years), and there were twice as many females as male. The most frequent causative foods were found to be apple, peach, kiwi, and melon in 13, 12, 12, and 11 patients, respectively. CAP frequency was shown to be similar to that of SPT regarding apple, whereas it was less than that of SPT regarding melon, peach, and kiwi. A significant correlation between the frequencies of SPT and CAP was found regarding apple (r=0.39, p<0.05) but not peach, kiwi, and melon. Forty-one of 63 patients with OAS (66.1%) had pollinosis and/or allergic rhinitis. In patients with OAS due to apple, the positive ratio of CAP response against alder pollen was higher than that in patients with OAS due to melon. In patients with OAS due to melon, the positive ratio of CAP responses against ragweed pollen, grass pollen, and mugwort pollen was higher than that in patients with OAS due to apple. Conclusion : In this study, positive ratios of SPT and CAP tended to differ according to the causative food, showing a smaller potential for reaction than might be suggested by patient history. Therefore, for the time being it would be more accurate to use a skin test for the diagnosis of OAS due to plant-derived foods.
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  • PROLONGED TYPE OF FOOD ALLERGY
    Takanori Imai, Takatsugu Komata, Mika Ogata, Morimitsu Tomikawa, Hiros ...
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1285-1292
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1285
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    Object : Prevalence of food allergy is the most frequent during infancy, and it is gradually decreasing with age. We can not distinguish patients developing tolerance from those with persistent food allergy, therefore we are unable to advice patients accelerating the development of tolerance. To clarify the factors developing tolerance or intolerance, we conducted the following study. Method : Patients who were diagnosed as food allergy to hen's egg, or cow's milk or wheat in infancy by the definitive history of positive food allergic reactions or food provocation tests were recruited to this study. Patients were divided into two groups ; one (prolonged group, n = 27) is those who needed to eliminate some of the main offending foods even at the age of 6 years old and the other (tolerized group, n = 37) is those who had released all main offending foods by the age of 6 years old. Result : The factors which distinguished the prolonged group from the tolerized group were the positive clinical history of the atopic dermatitis and its prolonged clinical course, past history of anaphylactic shock, and maximum number of offending foods in the past clinical history. The specific IgE against main antigens such as egg white, cow's milk and wheat in the tolerized group was lower compared to that in the prolonged group, whereas no significant difference was found in non specific IgE value, peripheral eosinophil counts, and specific IgE against other antigens. Conclusion : We could find the clinical factors discriminating food allergy patients against three major food allergen among children developing tolerance by the age of 6 years old form those without tolerance.
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  • A CASE OF MINOCYCLINE-INDUCED PNEUMONITIS WITH BILATERAL PLEURAL EFFUSION
    Satoko Arai, Yuka Shinohara, Yasuyuki Kato, Satoshi Hirano, Atsuto Yos ...
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1293-1297
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1293
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    A 51-year-old man was admitted to our hospital with fever, dry cough and dyspnea. He had taken minocycline for 11 days because of urinary tract infection. Chest X-ray on admission showed diffuse reticular shadows in bilateral lung fields with bilateral pleural effusion. Cessation of minocycline led to spontaneous improvement of symptoms and radiographic findings. The lymphocyte stimulation test for minocycline with peripheral blood and pleural effusion were negative. After provocation test with minocycline, he developed fever and dry cough and bilateral ground glass opacity appeared on his chest X-ray. He was diagnosed as minocycline-induced pneumonitis and recovered rapidly following corticosteroid therapy.
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  • A CASE OF ACUTE GENERALIZED EXANTHEMATOUS PUSTULOSIS CAUSED BY KERORIN^[○!R]
    Yukie Yoshida, Naoya Murayama
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1298-1300
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1298
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    A 78-year-old woman visited a local clinic because of cough and fever, and was prescribed levofloxacin, carbo-cisteine, and cold medicine (salicylamide, acetaminophen, anhydrous caffeine, promethazine methylene disalicylate). The following day, erythema appeared on the trunk, and spread. Multiple pustules independent of hair follicles developed on the erythema mainly in the skin folds. Histopathological examination revealed subcorneal pustular dermatosis. The clinical course and characteristics of the rashes led to a diagnosis of acute generalized exanthematous pustulosis (AGEP). Although the administration on levofloxacin, carbocisteine, and cold medicine were discontinued, the rashes recurred. We reviewed the patient's history, and found that she had a history of taking the over-the-counter drug Kerorin^[○!R], and had taken a dose of Kerorin^[○!R] on the day before the first examination and before the recurrence. The ingestion of Kerorin^[○!R] was regarded as an incidental oral administration test, which was positive. Thus, oral administration tests with Kerorin^[○!R] and its ingredients acetylsalicylic acid and anhydrous caffeine were positive, leading to a diagnosis of AGEP caused by Kerorin^[○!R].
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  • A CASE OF BEHCET'S DISEASE WITH FREQUENT RECURRENCE OF MULTIPLE PULMONARY ABSCESS-LIKE OPACITIES
    Hirokazu Nakajima, Hirochiyo Sawaguchi, Fumio Tsuji, Takeaki Miyamoto, ...
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1301-1305
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1301
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    A 39-year-old woman, who had a history of recurrent oral and genital ulcerations and folliculitis and had had a low-grade fever since December 2003, consulted our hospital on February 5, 2004. Chest radiography and computed tomography (CT) showed multiple pulmonary abscess-like opacities. She was admitted to the Department of Respiratory Medicine and Allergology, Kinki University School of Medicine on February 19, 2004. A transbronchial lung biopsy showed nonspecific inflammation with lymphocytic infiltration. The patient was discharged after she showed improvement with antibiotic therapy. She was readmitted to our hospital on October 3, 2006, because of recurrence of pulmonary abscess-like opacities. Bronchoalveolar lavage showed lymphocytosis (53%) but yielded no significant bacteria on culture. Behcet's disease was diagnosed on the basis of the three major symptoms (recurrent oral and genital ulcerations and folliculitis). The frequent recurrence of pulmonary lesions was suspected to be due to immunological impairment associated with Behcet's disease, and the pulmonary lesions and inflammatory reaction tests showed improvement after colchicine was administered. The patient was discharged on October 28, 2006. To our knowledge this is the third reported case of frequently recurrent multiple pulmonary abscess-like opacities in Behcet's disease.
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  • [title in Japanese]
    [in Japanese], [in Japanese], [in Japanese], [in Japanese]
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1306-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1306
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  • [title in Japanese]
    [in Japanese]
    Article type: Article
    2007 Volume 56 Issue 10 Pages 1307-1309
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1307
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1310-1328
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1310
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1329-1330
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1329
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1331-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1331
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1332-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1332_1
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1332-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1332_2
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1333-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1333
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1334-1335
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1334
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1336-1337
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1336
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1337-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1337
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1338-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1338
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1339-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1339
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1340-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1340_1
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1340-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1340_2
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  • [title in Japanese]
    Article type: Appendix
    2007 Volume 56 Issue 10 Pages 1340-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.1340_3
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  • [title in Japanese]
    Article type: Cover
    2007 Volume 56 Issue 10 Pages Cover6-
    Published: October 30, 2007
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.56.Cover6
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