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Article type: Cover
2007 Volume 56 Issue 12 Pages
Cover10-
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Article type: Cover
2007 Volume 56 Issue 12 Pages
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Masami Taniguchi
Article type: Article
2007 Volume 56 Issue 12 Pages
1475-1484
Published: December 30, 2007
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Yoko Kano
Article type: Article
2007 Volume 56 Issue 12 Pages
1485-1491
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1492-
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Hiroyuki Tsutsumi
Article type: Article
2007 Volume 56 Issue 12 Pages
1493-1497
Published: December 30, 2007
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Mitsufumi Mayumi
Article type: Article
2007 Volume 56 Issue 12 Pages
1498-1501
Published: December 30, 2007
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Yukinori Yoshida, Toshishige Inoue, Tomoki Nishikido, Makoto Kameda, I ...
Article type: Article
2007 Volume 56 Issue 12 Pages
1502-1509
Published: December 30, 2007
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The discontinuation of chlorofluorocarbon-beclomethasone dipropionate (CFC-BDP) products has made it necessary to switch to hydrofluoroalkane (HFA)-BDP. We studied the influence of the changing from CFC-BDP to HFA-BDP on pulmonary function in asthmatic children. Methods: In twenty asthmatic children (mean: 10.5 years of age) who were clinically well-controlled with CFC-BDP for longer than 6 months, CFC-BDP was switched to HFA-BDP, at half the dose of CFC-BDP. We examined the changes in spirometric parameters at 3-6 months after the switch. Results: FEV_<1.0>% ([FEV_<1.0>/FVC]×100) and % V_<50>([V_<50> measured/ V_<50> predicted]×100) were significantly improved (FEV_<1.0>%: pre 81.7±4.7→post 84.1±4.1[p<0.05], % V_<50>: pre 66.9±6.9→post74.4±11.3[p<0.05]). Comparison between patients with greater than 10% improvement in % V_<50> and those with less than 10% improvement revealed differences in the duration of using CFC-BDP (former 2.8±0.9 years, latter 5.2±2.4 years [p<0.05]) despite lack of difference in age at initiation of treatment with CFC-BDP. Conclusion: The changing from CFC-BDP to HFA-BDP showed the improvement of lung function in a part of asthmatic children. We should keep in mind that there are some differences of efficacy among the inhaled corticosteroid products. The long-term anti-inflammatory medication should be adjusted to normalize the pulmonary function on the basis of the degree of airway inflammation.
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Yorihisa Kotobuki, Hiroaki Azukizawa, Youko Nishida, Hiroyuki Murota, ...
Article type: Article
2007 Volume 56 Issue 12 Pages
1510-1514
Published: December 30, 2007
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We herein describe a 33-year-old female who recurrently exhibited urticaria accompanied by vomiting, diarrhea and dyspnea after taking red-colored food. From her history, we suspected the cochineal dye, the commonly used natural red dye in red-colored food and beverage, to be the cause of her symptoms. Oral provocation test using cochineal dye-stained red-colored boiled-fish-paste induced urticaria and respiratory symptoms. Furthermore the prick tests and the scratch tests with cochineal dye and carminic acid, the major ingredient of cochineal dye, were also positive. These results indicate that type 1 allergy to cochineal dye caused urticaria in this patient. Thereafter, she avoided the foods containing a cochineal dye and showed a complete clinical remission. Recently, the number of literatures described about increased incidence of type 1 allergy to cochineal dye. As the usage of cochineal dye is increasing in the Japanese market, we should keep in mind that cochineal dye can be a cause of urticaria in daily practice.
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Susumu Harada, Akiko Matsunaga, Rieko Miyachi, Taro Masaki, Tatsuya Mo ...
Article type: Article
2007 Volume 56 Issue 12 Pages
1515-1521
Published: December 30, 2007
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Background: Many cases of spice allergy have been reported especially from Scandinavian countries, but in contrast there are few reports in Japan. This time we experienced two cases of apiaceae spice allergy and practiced some kinds of examinations. We report here these two cases with the consideration concerning mechanizm of spice allergy. Methods and Subjects: We practiced 1) specific IgE of pollens and foods, 2) prick tests of spices and apiaceae vesitables, 3) immunoblot of spices, against two cases suspected spice allergy from their clinical courses. Clinically Case 1 32y.o. male had been no history of pollinosis, in contrast Case 2 46y.o. female had been suffered from pollinosis during spring and autumn seasons. Results: In Case 1 the scores of specific IgE of pollens were almost negative and immunoblot examination of spices revealed positive reaction at the site of 10〜12kDa and 60kDa. In Case 2 the scores of specific IgE of pollens were positive in many species and immunoblot examination of spices reacted positively at the site of 14kDa and 60kDa. Both of them showed positive reactions against many kinds of apiaceae spices in prick tests, so we diagnosed them as apiaceae spice allergy. Conclusion: According to these results we suspected Case 1 as class 1 allergy induced by the sensitization of spices themselvs and Case 2 as class 2 allergy caused by the cross reactions with pollinosis. So there may be some different mechanizms in the occurrence of spice allergy. In the future the occurrence of spice allergy will be supposed to increase and it will be necessary for us to pay much more attention to spice allergy even in Japan.
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[in Japanese]
Article type: Article
2007 Volume 56 Issue 12 Pages
1522-1524
Published: December 30, 2007
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1525-1537
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1538-
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1539-
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1540-
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1541-
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1542-1543
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1544-
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Article type: Index
2007 Volume 56 Issue 12 Pages
1545-1554
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Article type: Index
2007 Volume 56 Issue 12 Pages
1555-1558
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Article type: Index
2007 Volume 56 Issue 12 Pages
1559-1562
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1563-1564
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1565-1567
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1567-
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1568-
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1570-
Published: December 30, 2007
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
1570-
Published: December 30, 2007
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Article type: Appendix
2007 Volume 56 Issue 12 Pages
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Article type: Cover
2007 Volume 56 Issue 12 Pages
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Published: December 30, 2007
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