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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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Etsuko Takamura
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2009 Volume 58 Issue 6 Pages
613-619
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Keisuke Masuyama
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2009 Volume 58 Issue 6 Pages
620-629
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Kensei Naito
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2009 Volume 58 Issue 6 Pages
630-634
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Hajime Karasuyama
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2009 Volume 58 Issue 6 Pages
635-637
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Yutaro Kumagai, Tatsuya Saitoh, Shizuo Akira
Article type: Article
2009 Volume 58 Issue 6 Pages
638-647
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Atsushi Isozaki, Yutaka Kawano, Tetsuo Shoda, Akiko Yamaide, Norifumi ...
Article type: Article
2009 Volume 58 Issue 6 Pages
648-656
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Background and object: Two major convenient questionnaires of asthma control in childhood, Japanese Pediatric Asthma Control Program (JPAC) and Childhood Asthma Control Test (C-ACT) have been available in Japan. The aim of this study is comparison of utilities of these questionnaires by means of respiratory function and fractional nitric oxide (FE_<NO>). Subject and methods: The 154 samples from patients with asthma and their parents answered to two questionnaires at regular visits. At the same time, respiratory function and FE_<NO> were measured. The patients were divided into two groups according to the control levels defined by JPAC and C-ACT. The correlation of each total scores and respiratory function and FE_<NO> were examined. Results: The total scores of JPAC and C-ACT strongly correlated each other. Among 3 groups in JPAC the score of JPAC weakly correlated with %FEV_1, FEV_1/FVC and %MMF. In contrast there was no correlation between 2 groups C-ACT. FEV_1/FVC and %MMF were significantly different among the groups identified by the JPAC, but not among those by the C-ACT. Neither of the total scores of JPAC nor C-ACT correlated with FE_<NO>. Conclusion: JPAC and C-ACT may partially reflect the respiratory function, with preference to JPAC. In contrast, these questionnaires did not reflect FE_<NO>. Thus, physician should use these questionnaires with consideration of these points.
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Takefumi Yamaguchi, Kazuyuki Nakagome, Kiyoshi Udagawa, Yotaro Takaku, ...
Article type: Article
2009 Volume 58 Issue 6 Pages
657-664
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Background: Although adverse reactions to local anesthetics are often diagnosed as local anesthetic allergy, there is evidence that most of these reactions occur via non-allergic mechanisms. Methods: To evaluate allergic reactions to local anesthetics, challenge tests were performed in 20 patients who had a history of adverse events to local anesthetics for whom dental treatment was planned. The diagnostic protocol of this challenge test consisted of skin prick and intracutaneous tests, as well as subsequent incremental subcutaneous challenge tests with local anesthetics such as lidocaine. Results: 17 patients (85%) showed no immediate allergic response to lidocaine, which could then be used for dental treatment. Three patients (15%) reacted positively to lidocaine: one had local erythema at the site of the skin prick, and two reacted to subcutaneous challenge. Conclusion: The proportion of immediate-type reactions to local anesthetics is small but not rare in patients suspected of having local anesthetic allergy. This result suggests that the diagnostic approach to confirm allergy to local anesthetics is clinically important and requires further study in a larger population.
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[in Japanese]
Article type: Article
2009 Volume 58 Issue 6 Pages
665-669
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Article type: Appendix
2009 Volume 58 Issue 6 Pages
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Article type: Appendix
2009 Volume 58 Issue 6 Pages
671-672
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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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Article type: Appendix
2009 Volume 58 Issue 6 Pages
676-677
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Article type: Appendix
2009 Volume 58 Issue 6 Pages
678-679
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Article type: Appendix
2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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Article type: Appendix
2009 Volume 58 Issue 6 Pages
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Article type: Appendix
2009 Volume 58 Issue 6 Pages
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Article type: Appendix
2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
718-723
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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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2009 Volume 58 Issue 6 Pages
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Article type: Cover
2009 Volume 58 Issue 6 Pages
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