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2012 Volume 61 Issue 12 Pages
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2012 Volume 61 Issue 12 Pages
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Nobuyuki Kodani
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2012 Volume 61 Issue 12 Pages
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Masutaka Furue
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2012 Volume 61 Issue 12 Pages
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Makoto Kinoshita, Kiyoshi Takeda
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2012 Volume 61 Issue 12 Pages
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Shigeto Hamaguchi, Masafumi Seki, Kazunori Tomono
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2012 Volume 61 Issue 12 Pages
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Naomi Kondo, Eiko Matsui, Hidenori Ohnishi, Takahide Teramoto, Zenichi ...
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2012 Volume 61 Issue 12 Pages
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Tomoya Harada, Yuji Kawasaki, Hirokazu Touge, Hirokazu Tokuyasu, Akira ...
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2012 Volume 61 Issue 12 Pages
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A 33-year-old man complaining of cough admitted our hospital for examination of bilateral hilar and mediastinal lymphadenopathy. He diagnosed pulmonary sarcoidosis, because of elevation of serum angiotensin converting enzyme (ACE), epitheloid granuloma with noncaseating necrosis from transbronchial lung biopsy (TBLB) specimen, increasing of lymphocyte and elevation of the CD4/CD8 ratio in bronchoalveolar lavage fluid (BALF). Furthermore, eosinophil ratio in BALF was 3%, hyperplasia of goblet cell, eosinophilic invasion to bronchial epithelium, and thickened basal membrane were found in same biopsy specimen. He had mild reversible airway obstruction. He was diagnosed pulmonary sarcoidosis complicated with bronchial asthma. Sarcoidosis is characteristic of the T helper type 1 (Th1) mediated immune response, and bronchial asthma is characteristic of the Th2. This case histopathologically revealed that both Th1 mediated immune response and Th2 could be coexisted.
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2012 Volume 61 Issue 12 Pages
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Article type: Appendix
2012 Volume 61 Issue 12 Pages
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2012 Volume 61 Issue 12 Pages
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2012 Volume 61 Issue 12 Pages
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2012 Volume 61 Issue 12 Pages
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2012 Volume 61 Issue 12 Pages
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Article type: Cover
2012 Volume 61 Issue 12 Pages
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