Japanese Journal of Allergology
Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884
Search
Advanced search
OR
Browse
Search
Volume 65, Issue 7
Displaying 1-12 of 12 articles from this issue
Show all abstracts
    • |<
    • <
    • 1
    • >
    • >|
Allergology Course For Allergy Specialists—Management of allergies in group lives
One Point Reviews of Allergy Guidelines
Review Article
Original Article
  • A STUDY OF INSPIRATORY RESISTANCE OF DRY POWDER INHALER OF AGENTS FOR ASTHMA CONTROL
    Shigeaki Suda, Rio Konno, Hajime Kurosawa, Gen Tamura
    2016 Volume 65 Issue 7 Pages 932-936
    Published: 2016
    Released on J-STAGE: August 20, 2016
    DOIhttps://doi.org/10.15036/arerugi.65.932
    JOURNAL FREE ACCESS
    Show abstractHide abstract

    Objective: Because dry powder inhalers (DPI) aerosolize agents by means of inspiration of patients themselves, inspiratory resistance of DPI is an important factor for increasing inhalation efficiency. Therefore, we measured inspiratory resistance of DPI of agents for asthma control.

    Methods: Using Flow/Volume Simulator, when setting flow rates at 6, 30, 60, 90, and 120L/min, we read off suction pressures and find inspiratory resistances by calculation (=suction pressure/flow rate) at each flow rate.

    Results: In all DPI, inspiratory resistance increases with the increasing flow rate. To maintain flow rate of 60L/min, suction pressure of around 20-cmH2O for Diskus® and Ellipta®, between 35- and 45-cmH2O for Turbuhaler ®, and about 60-cmH2O for Twisthaler® were needed.

    Conclusion: It is suggested that we should instruct patients to inhaler DPI based on inspiratory resistance of the DPI.

    View full abstract
    Download PDF (299K)
Case Report
  • OMALIZUMAB RESCUED A ASTHMA-COPD OVERLAP SYNDROME PATIENT FROM A STATUS ASTHMATICS UNDER THE ICU MANAGEMENT
    Shunichi Gamo, Hideya Iijima, Yumika Seki, Ryo Horaguchi, Yuji Suda, Y ...
    2016 Volume 65 Issue 7 Pages 937-941
    Published: 2016
    Released on J-STAGE: August 20, 2016
    DOIhttps://doi.org/10.15036/arerugi.65.937
    JOURNAL FREE ACCESS
    Show abstractHide abstract

    An atopic asthmatic of 65-year-old man who was complicated with COPD and treated with inhaled corticosteroid, long-acting β2 agonist, long-acting muscarinic antagonist, and leukotriene receptor antagonist was hospitalized with a severe asthmatic attack. He was intubated and went onto an artificial respirator. He was gradually relieved by repeated intravenous administration of high-dose corticosteroid, and a respirator was switched over to non-invasive positive pressure ventilation on 24th day. However, he repeated asthmatic attacks which needed corticosteroid to recover. Omalizumab was administered on 35th day and asthmatic attacks remarkably decreased. He left the hospital on 71st day. It was thought that the additional administration of omalizumab provided a good clinical response for an intractable asthma.

    View full abstract
    Download PDF (398K)
Report
    • |<
    • <
    • 1
    • >
    • >|
feedback
 Top