アレルギー
Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884
9 巻, 10 号
選択された号の論文の7件中1~7を表示しています
  • 原稿種別: 目次
    1960 年 9 巻 10 号 p. 1008-1011
    発行日: 1960/10/01
    公開日: 2016/10/20
    ジャーナル フリー
  • 龜田 通夫
    原稿種別: 本文
    1960 年 9 巻 10 号 p. 783-789,1
    発行日: 1960/10/01
    公開日: 2016/10/20
    ジャーナル フリー
    Fifteen groups of mice (ddN, CF#1, CFW and gpc) were immunized by intraperitoneal, intramuscular or intravenous injection of the heat killed tubercle bacilli (H_<37>RV) or the BCG vaccine. Pooled sera were prepared by cardial puncture from five mice at weekly intervals. Serum sample were examined by Middlebrook-Dubos' passive hemagglutination, conditioned hemolysis and Sindo-Utahashi's modified Coombs' test using tuberculin fractions as the antigens. It was proved that production of specific antibodies against tubercle bacilli in mice, in general, was very low. In cases of immunized mice with the heat killed organisms, no antibodies could be found by those testings in vitro. But serum samples obtained from mice immunized with BCG at the 7-9th week were proved to be definitely positive in the hemolytic reaction and the modified Coombs' test in which the incomplete antibodies are thought to participate. No bivalent antibodies, as a whole, could be detected by those methods under given conditions. Amongst several sorts of mice, CF#1 is considered to be most sensitive and homogeneous in production of antibodies against tubercle bacilli.
  • 船津 清
    原稿種別: 本文
    1960 年 9 巻 10 号 p. 790-797,1
    発行日: 1960/10/01
    公開日: 2016/10/20
    ジャーナル フリー
    Eight groups of mice were immunized by single or repeated injections of the heat killed organisms of S. enteritidis. Pooled sera were prepared by cardial puncture from five mice at weekly intervals after immunization. Serum samples were examined by Middle brook-Dubos' passive hemagglutination, conditioned hemolysis and Sindo-Utahashi's modified Coomb's test by the use of the soluble antigen fraction derived from the organism. At the same time, the bacillary agglutination was tested also following the conventional Widal test. The incomplete antibodies which are thought to participate mainly in the hemolytic reaction, were proved to be produced dominantly and earlier than the complete antibodies. The agglutinin could not be detected in serum samples obtained from mice immunized by a single injection, while the samples prepared from the groups which were immunized by repeated injections of small amount of the organism, reacted positively in the agglutination. It is considered, therefore, that the incomplete antibodies may play an important role also in immunological studies of mice in salmonellosis.
  • 芳賀 邦夫, 龜田 通夫, 船津 清
    原稿種別: 本文
    1960 年 9 巻 10 号 p. 798-800,2
    発行日: 1960/10/01
    公開日: 2016/10/20
    ジャーナル フリー
    Using purified tuberculoprotein preparations PPD-s, π and TA_2 which are considered to have nearly the same purity as PPD-S (Seibert) and tuberculopolysaccharide preparations (D from Dr. Popp, TA_2 and Fr. II), antigenic potencies of these preparations in the passive hemagglutination and conditioned hemolysis were compared by the three-dimensional analysis. Three polysaccharide preparations, of course, were proved to have distinct potency in both reactions, but three tuberculoprotein preparations reacted also apparently positively in both reactions without applying the Boyden's technique.
  • 木沢 健一
    原稿種別: 本文
    1960 年 9 巻 10 号 p. 801-835,2-3
    発行日: 1960/10/01
    公開日: 2016/10/20
    ジャーナル フリー
    The skin test was carried out by measaring the extent of pale sphere as the reaction of intradermal injection of 0.01% solution of noradrenaline in 1,618 cases of healthy individuals and of patients suffering from various kinds of diseases, and discussed the relationship between the reaction and the condition of autonomic nervous system of individuals. Healthy 167 individuals who had suffered from neither allergic diseases nor disorders of autonomic nervous system in the past, were examined as controls. There was no significant distinction of sex in the test but the degree of the reaction increased as the advance of ages. As to seasonal influences on the test, there was observed only slight seasonal fructuation in the control group, while healthy persons who had the past history of allergic diseases or disorders of of autonomic nervous system, showed a marked seasonal fructuation; the reaction strong in winter, but weak in summer. Cases suffering from hypertention, organneurosis, vegetative dysharmony, climacteric disturbance, hyperthyroidism, disorders of liver or gall-bladder and tuberculosis of the lung showed stronger reaction, and patients of bronchial asthma, peptic ulcer and hypotention showed slightly stronger reaction than the reaction of the control group. Cases of painful stadium of rheumatism and eruption stage of urticaria or contact dermatitis showed weaker reaction than the controls. Among cases of neuralgia, decompensatory heart failure, malignant tumor and anemia, patients with history of allergic diseases in the past showed stronger reaction than patients without such history. Among healthy individuals, further, persons with history of allergic diseases showed stronger reaction than persons without such history. It seemed that the reaction varied with the process of the disease. In cases of organneurosis, vegetative dysharmony, climacteric disturbance, hypertention, hyperthyroidism and so on, the reaction decreased gradually following the effect of medical treatment. In cases of bronchial asthma and urticaria, the reaction decreased during the fit of asthma and course of urticaria than before or after them. Noradrenaline intradermal test showed positive correlation between the systolic or diastolic blood pressure, and negative correlation between the capillary resistance or acetylcholine insradermal test. Either stimulation of the sympathetic nerve with sympathomimetic drugs or inhibition of the parasympathetic nerve with parasympathomimetic drugs intensified the reaction. On the contrary, when the sympathetic nerve function was inhibited or parasympathetic nerve function was stimulated, the reaction was inhibited. Summarizing the results, it might be conclude than noradrenaline intradermal test shows strong reaction in sympathiocotomic persons as well as the persons whose function of the autonomic nerveis labile.
  • 七条 小次郎, 小林 節雄, 田中 今朝昭, 中沢 精二, 大沢 雄二郎, 笛木 隆三, 近藤 忠徳, 中村 篤, 柁原 昭夫, 金子 由之 ...
    原稿種別: 本文
    1960 年 9 巻 10 号 p. 836-840,2
    発行日: 1960/10/01
    公開日: 2016/10/20
    ジャーナル フリー
    In an attempt to clarify the nature of Konjac Bronchial Asthma, clinical studies have been made in three patients with bronchial asthma definitely caused by"Maiko". In all three patients, skin test and Prausnitz-Kustner reaction by protein extract of "Maiko", showed an immediate reaction. By the use of the Boyden's technique, antibody against"Maiko"was detected in the serum of all patients. In one of three patients, typical asthma attack could be produced not only by actual ingestion but also by suggesting that he is taking Amorphophalus Konjac without actual addition of it to the diet. Asthma attack on these patients could be produced by inhalation of"Maiko"or its extract, but much time elapsed before typical asthma attack comparing to the result of the previous report.
  • 原稿種別: 文献目録等
    1960 年 9 巻 10 号 p. 1-3
    発行日: 1960/10/01
    公開日: 2016/10/20
    ジャーナル フリー
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