The distribution of the Gc groups was investigated on 178 Thai adults, all of whom were in Central Chest Hospital, Bangkok, with tuberculosis. The phenotype frequencies were: Gc 1-1 66.85%, Gc 2-1 28.65% and Gc 2-2 4.49%. The goodness of fit was tested by the following equation: x
2=n(c
2-4bd)
2/(2b+c)
2(c+2d)
2 (d. f.=1) where, b, c and d meant the observed number of Gc 1-1, Gc 2-1 and Gc 2-2 respectively.
The results of test (x
2=0.6917, 0.50>P>0.30) indicate that the distribution is in an agreement with HARDY-WEINBERG's law.
The gene frequencies calculated by maximum likelihood method were : Gc
1=0.8118±0.0207 and Gc
2=0.1882±0.0207. The frequency of gene Gc
1 was higher than that of the Japanese (0.7730-0.7753; ISHIMOTO, 1963, OMOTO
et al., 1964), Koreans (0.7586; OMOTO
et al., 1964) or the Chinese (0.7693; CLEVE and BEARN 1961).
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