A total of about six hundred individuals living in Kamishima Island, Mie Prefecture have been tested for genetic variation in two blood groups, four serum protein and twelve red cell enzyme systems, namely, ABO, Rh-Hr;Hp, Tf, IgG (Gm and Km); AcP, PGM, GPT, PGD, EsD, ADA, PHI, GOT, LDH, PGK, AK and PepA. **
An appreciable polymorphism in each trait, except for LDH, PGK, AK and PepA systems, was observed.
The genetic characteristics of this population and the difference between the neighbouring populations is discussed.
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