Pure Adenine, prepared from dry yeast does not serve as a source of Vitamin B
4 in the albino-rat. Since it has been shown repeatedly that the feeding of large amounts of adenine neither prevents nor cures the typical symptoms of Vitamin B
4 deficiency.
My thanks are due to Proffesor U. Suzuki for his advice and interest throughout the work to Dr. S. Ohdake for the supply of oryzanin, Vitamin B
1 concentrates and to Mr. H. Ariyama for his continued help in this experiment.
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