1) The present study was carried out to clarify a mechanism of the formation of the silkprotein during the growth of the silkworm larva.
2) A large part, about 70 per cent of the silkproteins produced by one silkworm is directly derived from the proteins of the mulberry leaves (direct formation), but some part of the silkproteins, about 30 per cent, is also derived from the tissue proteins and body fluid proteins, in relation to the metamorphosis of the silkworm larva (indirect formation); there are two pathways in the formation of the silkproteins during the growth of the silkworm larva, i.e., direct formation and indirect formation.
3) The direct formation of the silkproteins takes place, in the hybrids of Japanese race and Chinese race, during the period between the 4th day of the 5th instar and maturity, but the indirect formation takes place during the period from the 8th day of the 5th instar to just before termination of spinning after reaching maturity. My thanks are due to Mr. Mitsumasa Suto, Mr. Motoichi Matuda, Mr. Tsutomu Kurose and Mr. Yoshiaki Horiuchi for their skilful technical assistance in the current work,
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