Bioscience and Microflora
Online ISSN : 1349-8355
Print ISSN : 1342-1441
ISSN-L : 1342-1441
23 巻 , 3 号
July
選択された号の論文の1件中1~1を表示しています
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  • Hiroshi OHNO, Yoko ISHIHARA, Teruhiko ARAI, Hideki YAMAMURA, Nagao TOT ...
    原稿種別: Others
    専門分野: Others
    2004 年 23 巻 3 号 p. 109-117
    発行日: 2004年
    公開日: 2005/03/04
    ジャーナル フリー
    Bifidobacterium bifidum G9-1 (BBG9-1) was administered orally to ExHC (Exogenously Hypercholesterolemic) rats, Wistar fatty rats and KK-Ay mice, and the effect on the lipids of the plasma and liver was found to be as follows. 1) BBG9-1 significantly reduced the levels of cholesterol and triglyceride in the plasma and liver of ExHC rats fed a cholesterol-enriched diet. In addition, the cholesterol level of low-density lipoprotein (LDL), and the cholesterol and triglyceride levels of very low-density lipoprotein/chylomicron (VLDL/CM) were lower in the BBG9-1-administered rats than in the control rats. 2) In Wistar fatty rats, BBG9-1 significantly decreased the levels of cholesterol and triglyceride in the liver but not those in the plasma. 3) In KK-Ay mice, BBG9-1 significantly reduced not only the levels of cholesterol and triglyceride in the plasma and liver, but also the plasma glucose level. These results suggest that BBG9-1 lowers elevated levels of blood lipids and/or hepatic lipids in hypertriglyceridemia, hypercholesterolemia and hyperglycemia.
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