巻号一覧
32 巻, 1 号
選択された号の論文の12件中1～12を表示しています
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Über Einflüsse der Bestrahlung der Milz mit Ultraviolett- und Röntgenstrahlen auf den Zusammenhang zwischen Kephalin- und Proteinfraktion im Blutplasma des KaninchensNORIO YOSIDA1940 年 32 巻 1 号 p. 1-9
発行日: 1940年
公開日: 2008/06/30
ジャーナル フリーObige Ergebnisse kann man folgenderweise zusammenfassen.
Die Ultraviolettbestrahlung der Milz ruft eine temporäre Vermehrung von Kephalin hervor, die sich aber nach 24 Stunden noch bedeutender vermindert als vor der Behandlung.
Im Gegensatz dazu ruft die Röntgenbestrahlung eine bedeutende Vermehrung des Kephalins hervor, die auch noch nach 24 Stunden eine zunehmende Tendenz behält. Beim Kontrollversuch mit. exstirpierter Milz ist das nicht der Fall. Dieser Unterschied erscheint bei der Röntgenbestrahlung besonders deutlich.
Es entsteht die Frage, was für eine Korrelationsbeziehung zwischen der Kephalinverwandlung und Eiweissstoff besteht. Zwischen Euglobulin und Kephalin scheint eine gewisse Beziehung zu bestehen, weil nämlich durch Röntgenbestrahlung der Milz sich Kephalin vermehrt, während Euglobulin sich dadurch vermindert. Dieselbe Beziehung aber kann man bei der Ultraviolettbestrahlung nicht bemerken, aber 24 Stunden nach der Bestrahlung vermindert sich Kephalin, wobei Euglobulin sich vermehrt.抄録全体を表示PDF形式でダウンロード (423K) -
I. Experimental studies on blood acetaldehyde. II. Clinical investigations on blood acetaldehydeKOKUSHO RI1940 年 32 巻 1 号 p. 11-55
発行日: 1940年
公開日: 2008/06/30
ジャーナル フリーThe experimental and clinical results on blood acetaldehyde can be summarised as follows:
1. After giving glucose, both blood acetaldehyde and blood sugar gradually increase and the former reaches its maximal value after two or three hours. We can see almost the same results after the giving of fructose.
2. Upon providing glucose to dogs nourished with a proteinfat diet, under a fasting condition or poisoned with carbon tetrachloride, the dietary hyperglycemia appeared stronger than in cases of mixed diet. The maximal increase value of blood acetaldehyde was just the opposite, being smaller than in cases of mixed diet.
3. When fructose was given to dogs fed on a protein-fat diet, in a fasting condition or poisoned with carbon tetrachloride, the disturbances of the fructose metabolism were noticeable, and the maximal increase value of the blood acetaldehyde in each case is smaller than in that of a mixed diet.
4. When fructose was given to dogs in normal condition or under experimental disturbances of sugar metabolism, the maximal increase value of blood acetaldehyde was larger than that after the giving of glucose.
5. The maximal increase value of the blood acetaldehyde increases after insulin injection and decreases when adrenalin is injected.
6. The maximal increase value of blood acetaldehyde of patients with diabetes mellitus was in all cases smaller than that of healthy persons. Moreover, the higher the hyperglycemia of the patients was, the smaller were the maximal increase values.
7. Among patients with Basedow's disease, pulmonary tuberculosis and diseases of the liver and the gall-bladder system, those who had disturbances of the sugar metabolism showed a smaller maximal increase value of blood acetaldehyde than that of normal persons.
8. In my experimental as well as clinical investigations, the maximal increase value of blood acetaldehyde of individuals having disturbances of the sugar metabolism was smaller than that of normal cases, That is, when disturbances of the sugar metabolism are seen, a hindrance of the oxydation of sugar also exists.
In closing I wish to express my heartiest thanks to my esteemed director, Prof. Dr. Kageura for his kind efforts in directing this research. I wish also to express my deepest gratitude to assistant Prof. Dr. Hara for his kind assistance.抄録全体を表示PDF形式でダウンロード (1752K) -
TORASABURO INAGAKI1940 年 32 巻 1 号 p. 57-62
発行日: 1940年
公開日: 2008/06/30
ジャーナル フリーAttempts were made to find reagents which would precipitate nucleotides, nucleosides, and purine and pyrimidine bases quantitatively, but leave pentoses and their phosphoric esters in solutions.
The results so far obtained are summaried in the table. Mercuric nitrate was found to be the most useful precipitant. It precipitated the nitrogen-containing substances quantitatively, irrespective of the nature of the bases and the pentoses. Mercuric sulphate and acetate were also available for the study of the hydrolysis of yeast amino-purine nucleotides.抄録全体を表示PDF形式でダウンロード (280K) -
TORASABURO INAGAKI1940 年 32 巻 1 号 p. 63-79
発行日: 1940年
公開日: 2008/06/30
ジャーナル フリーThe hydrolysis of desoxyribo-nucleotides and -nucleosides by acid and enzymes was studied.
1. Desoxyribo-guanylic and -adenylic acids were sensitive to acid hydrolysis at the glycosidic linkages. However, the susceptibilities were not so high as had been supposed to be. The ester linkages were extremely resistant to hydrolysis. Desoxyribocytidylic acid was also easily hydrolyzed at its glycosidic union.
2. The aqueous extract of rabbit muscle disrupted only the glycosidic linkages of purine desoxyribo-nucleotides. The kidney extract hydrolyzed both linkages, showing higher affinity to the ester union. The liver extract held the intermediate situation between the muscle and kidney extract with respect to the hydrolysis. The intestinal juice of dogs attacked the ester linkages only.
Pyrimidine desoxyribo-nucleotides were quite resistant to the hydrolysis by the muscle extract. However, the ester linkages were easily disrupted by the kidney and liver extracts and by the intestinal juice, glycosidic unions being unaffected.
3. The high sensitivity of purine desoxyribo-nucleosides to acid was confirmed. Pyrimidine nucleosides were also hydrolyzed by acid. Desoxyribo-guanosine was a little more susceptible to the hydrolysis by kidney enzyme than ribo-guanosine.
4. The N-condensation products of desoxyarabinose with aniline, and of desoxyglucose with aniline, isomeric toluidines and xylidines, were synthesized. The hydrolysability of these N-desoxyglycosides were greater than that of corresponding glycosides. The influence of the structure of aglucones on the hydrolysability of N-desoxyglucosides was studied.抄録全体を表示PDF形式でダウンロード (794K) -
TAKASI SASAKI1940 年 32 巻 1 号 p. 81-86
発行日: 1940年
公開日: 2008/06/30
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TAKASI SASAKI1940 年 32 巻 1 号 p. 87-90
発行日: 1940年
公開日: 2008/06/30
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3. Mitteilung. Über die Affinität der Hexosidase zu Hexose und HexosidSHIGERU EZAKI1940 年 32 巻 1 号 p. 91-105
発行日: 1940年
公開日: 2008/06/30
ジャーナル フリーEs wurde der Einfluss der Hexosen und Hexosiden auf die fermentative Hydrolyse der p-Nitrophenol-hexoside untersucht. Der Hydrolysengrad wurde aus denj kolorimetrisch bemessenen freien p-Nitrophenol bereehnet. Man kann in den β-Hexosidasen 2 Arten von Fermenten, nämlich von Taka- bzw. Emulsin-Typus, unterscheiden. IIinsichtlich der α-Glukosidase wurde, so weit es sick um den Hemmungsversuch handelte, nur eine Art Ferment nachgewiesen. Die Wirkung der Glukose, Galaktose und ihrer Phenolhexoside auf die Wirkung der Takadiastase und des Emulsins wird in der folgenden Tabelle zusammengestellt.抄録全体を表示PDF形式でダウンロード (642K) -
4. Mitteilung. Über die β-Glukosidasehemmung der α-Glukoside und GlukonsäureSHIGERU EZAKI1940 年 32 巻 1 号 p. 107-120
発行日: 1940年
公開日: 2008/06/30
ジャーナル フリーDie Wirkung des Ferments vom Takatypus auf p-Nitrophenol-β-glukosid wird nicht nur durch Glukose oder β-Glukoside, sondern auch durch α-Glukoside und Glukonsäure gehemmt. Der hemmende Einfluss wird auch von Glukonsäureäthylester und in sehr starkem Grad von Glukonsäurelakton ausgeübt. Eine schwache Hemmung des Glukonsäureamids ist dem daraus spontan entstehenden Lakton oder Glukonat zuzuschreiben. Das Amid zerfällt spontan zuerst in Lakton und Ammoniak, das Lakton wird dann in Glukonat umgewandelt.
Glukonsäure hemmt weder die β-Galaktosidspaltung vom Emulsintypus noch die α-Glukosidase.抄録全体を表示PDF形式でダウンロード (577K) -
II. A modification of Folin's method for the determination of aminonitrogen by means of β-naphthoquinone-4-sulfonic acidTETURÔ HORI1940 年 32 巻 1 号 p. 121-130
発行日: 1940年
公開日: 2008/06/30
ジャーナル フリーAn improved micro-method for the determination of aminonitrogen by means of β-naphthoquinone-4-sulfonate is reported.
Many thanks are due to Prof. K. Kodama for his kind criticisms and suggestions.抄録全体を表示PDF形式でダウンロード (308K) -
HIDEO ISAKA1940 年 32 巻 1 号 p. 131-135
発行日: 1940年
公開日: 2008/06/30
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HIFUMI HORIE1940 年 32 巻 1 号 p. 137-160
発行日: 1940年
公開日: 2008/06/30
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CHIKASUKE YAMAMOTO1940 年 32 巻 1 号 p. 161-173
発行日: 1940年
公開日: 2008/06/30
ジャーナル フリー1. From the viewpoint of metabolism it is of extreme importance to determine the various sugar values (hydrolysable sugar and free sugar) in the blood at the same time, and a method has been described for the determination of the various sugar values.
2. By this method orcinol reacts only to sugar, and comparing with the reduction method of determining the hydrolysable sugar in the blood by employing yeast, more accurate and brief calculation is possible.
3. There is a marked difference in the value of free true sugar in the blood of different animals; while in value of hydrolysable sugar there was no great difference, with the exception of pigs.
4. The values of free true sugar and hydrolysable sugar in the blood of such animals as pigs, rabbits, guinea pigs and mice indicate the same; but in the instance of cows, horses, goats, chickens and pigeons we found marked difference.
5. The averages of various sugar values in the blood-serum of a normal rabbit are: of free true reducing sugar, 135mg%; of deprotein. orcinol sugar, 153mg%; of hydrolysable sugar, 149mg%. The value of free true reducing sugar in the total blood is 102mg%, of deprotein. orcinol sugar, 153mg%.
6. The contents of sugar value within the blood of a fasting rabbit can be divided into cases in which the values of the free true reducing sugar (and of hydrolysable sugar) correspondingly decrease, and other cases in wihch they increase. There are cases also in which the value of free true sugar alone increases, and other cases in which hydrolysable sugar alone decreases.抄録全体を表示PDF形式でダウンロード (539K)
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