Transcription of human adenovirus genes is regulated by a variety of cellular and viral transcription factors. We described in this issue recent informations of adenovirus E1A proteins, and cellular factors, TF II D, ATF/E4TF3, E2F, E4TF1 and USF, responsible for transcription of adenovirus genes. In addition to the transcription factors, we introduced a newly concept of initiator, which is a transcription control element of adenovirus major late promoter.
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