Inner-arm dynein subspecies c (dynein c) of
Chlamydomonas flagella is the single-headed dynein which is capable of generating force on microtubules. We recently found that dynein c is a processive motor: a single molecule of dynein c is required to move a microtubule more than 1 μm. However, the duty ratio of dynein c,
i.
e. the proportion of strongly attached to total ATPase cycle, was estimated to be
ca. 14%. This feature is distinct from that of kinesin which is known to be a two-headed processive motor with the higher duty ratio.
View full abstract