生物物理
Online ISSN : 1347-4219
Print ISSN : 0582-4052
ISSN-L : 0582-4052
43 巻 , 4 号
通巻248号
選択された号の論文の7件中1~7を表示しています
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  • 津下 英明
    原稿種別: 研究論文
    専門分野: 情報学
    2003 年 43 巻 4 号 p. 168-173
    発行日: 2003年
    公開日: 2003/07/23
    ジャーナル フリー
    The family of mono-ADP-ribosyltransferase includes not only bacterial toxins but also mammalian enzymes. Recently, crystal structures of arginine-specific ADP-ribosyltransferase have been revealed, giving a better understanding of type IV toxin. They are VIP2 from Bacillus and Ia from Clostridium perfringens. VIP2 and Ia ADP-ribosylate the Arg177 of actin. They consist of topologically similar N- and C-domains, which have not been expected from the amino acid sequence. C-domain is an enzymatic domain. N-domain interacts with VIP1 and Ib, respectively. C-domain structures were basically the same but the surface charge of N-domain was found significantly different between VIP2 and Ia. Rat ART2.2 and rho-targeted C3 toxin(asparagine-specific)consist of only one domain and the structure is similar to the C-domain of Ia. We summarize the crystal structure and the reaction mechanism of Ia.
  • 笠原 賢洋, 和田 正三
    原稿種別: 研究論文
    専門分野: 情報学
    2003 年 43 巻 4 号 p. 174-179
    発行日: 2003年
    公開日: 2003/07/23
    ジャーナル フリー
    Two kinds of blue-light receptors, cryptochrome and phototropin, have been found in higher plants. Cryptochrome mediates the inhibition of hypocotyl elongation and anthocyanin accumulation, and controls the timing of flowering and the circadian clock. Phototropin mediates phototropism, light-dependent chloroplast movement, stomata opening and leaf expansion. Here we review the characteristics of these photoreceptors and the signal transduction mechanisms downstream of the blue-light receptors.
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