Taste bud cells senses taste substances even if they separately occur on tongues. However, taste bud cells gather to form taste buds.
In-situ patch clamp recordings showed that mouse taste bud cells elicited either depolarizing or hyperpolarizing receptor potentials in response to taste stimuli, and in-situ optical recordings revealed a tendency that mouse taste bud cells gather by the polarity of their receptor potentials. They expressed functional gap junctions, glutamate receptors, and serotonin receptors on their basolateral membranes. It is likely that mouse taste bud cells make cell networks to regulate taste transduction mechanisms.
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