THE BULLETIN OF TOKYO MEDICAL AND DENTAL UNIVERSITY
Online ISSN : 2435-0761
Print ISSN : 0040-8921
17 巻, 3 号
選択された号の論文の6件中1~6を表示しています
  • II. Digestion of Melanosome with Mouse Liver Lysosome
    Noriko OHTAKI
    1970 年 17 巻 3 号 p. 179-186
    発行日: 1970年
    公開日: 2022/11/12
    ジャーナル オープンアクセス
    Swiss mice bearing melanomas received intraperitoneal injection of 14C-amino acid mixture and 14C-DOPA separately. Radioactive mitochondria and melanosomes were isolated from these mouse melanomas. In vitro degradation of 14C-amino acid labeled melanosomes and mitochondria was carried out with lysosomes isolated from mouse liver. The progressive degradation of protein moiety of mitochondria was observed and the slow but steady degradation of melanosomes was also brought about. In vitro degradation of 14C-DOPA labeled melanosomes was performed with liver lysosomes. There was no significant amount of degradation in vitro. From these experimental results, immature, less melanized melanosomes would be more susceptible than the mature, fully melanized melanosomes. It is assumed, therefore, that in the phagosomes, melanosomes can be degraded by lysosomes at the protein moiety and the mature melanosomes would be more resistant against lysosomal attack.
  • Sinsak HORIGUTI, Yuzuru TANIKAWA
    1970 年 17 巻 3 号 p. 187-215
    発行日: 1970年
    公開日: 2022/11/12
    ジャーナル オープンアクセス
    The present study has been performed, in order to elucidate the relationship between inflammation of the nasopharyngeal mucosa and the flora, and agents aggravating inflammation. The results were as follows: 1) There was a parallel relation between the change of the nasopharyngeal flora and clinical symptoms of nasopharyngitis, especially at the time of acute exacerbation of nasopharyngitis. The change of the flora on smears was divided into 6 grades. 2) The cultural characteristics of the flora were divided into 3 types according to the growing mode on the blood agar. The characteristics of the flora had close relations with clinical course of nasopharyngitis. 3) The strain, especially staphylococcus aureus, whose colony frequently showed pure culture on the blood agar was considered as one of the agents aggravating nasopharyngitis. 4) The experiment in rabbits revealed the staphylococcus aureus alone could cause slight nasopharyngitis, but more severe inflammation caused by the bacteria was applied to the nasopharynx with the powder of charcoal. Consequently, it is thought that dust can play an important role in exacerbation of nasopharyngitis.
  • Masatoshi TANAKA, Tamenobu KUBOTA, Hiromasa KITA
    1970 年 17 巻 3 号 p. 217-226
    発行日: 1970年
    公開日: 2022/11/12
    ジャーナル オープンアクセス
    This study was carried out to know the physiological reaction to cold of swimmers, acclimatized to cold. Experiments were made on four healthy adult males aged 25 to 28 years, two excellent swimmers and two students being in the nude and seated on a stool in the climate chamber adjusted to a room temperature of about 12℃. Heat production, rectal temperature, and skin temperature were measured and the following results were obtained. 1. Increase of heat production was remarkably small in the swimmers and the onset of shivering was observed late or not shown. 2. The rectal temperature and the mean skin temperature of the swimmers were lower than that of the control group, and the rate of temperature fall was greater than that in the control group. 3. There was no great difference in the peripheral extremity skin temperature between the two groups.
  • Isamu NAKAZAWA, Hiroshi AMEMORI
    1970 年 17 巻 3 号 p. 227-237
    発行日: 1970年
    公開日: 2022/11/12
    ジャーナル オープンアクセス
    Owing to the formidable number of attachments, we cannot assess the relative merit of all these units and choose the most effective attachment when indicated. Therefore, it has been thought advisable to devise a classification. In this paper the authors propose a new classification of attachments. This classification is based on three characteristics of the attachments. The first step is to classify attachments into coronal and radicular attachments. The next step is to divide the former into intracoronal and extracoronal attachments, and the latter into intraradicular and extraradicular attachments. Finally, they are each classified into precision type and stress-breaking type. Consequently, attachments are classified into the following eight groups: (1) The precision type of intracoronal attachment. (2) The stress breaking type of intracoronal attachment. (3) The precision type of extracoronal attachment. (4) The stress-breaking type of extracoronal attachment. (5) The precision type of intraradicular attachment. (6) The stress-breaking type of intraradicular attachment. (7) The precision type of extraradicular attachment. (8) The stress-breaking type of extraradicular attachment.
  • Hideo ITO, Tadao SODA, Akihito ASAKURA, Tamio NAKAJIMA, Yoji KOBAYASHI ...
    1970 年 17 巻 3 号 p. 239-247
    発行日: 1970年
    公開日: 2022/11/12
    ジャーナル オープンアクセス
    An unusual case of a salivary gland tumor which was formed in the mandible is described. The tumor was successfully removed by block resection of the ascending ramus of the mandible and histologically diagnosed as an acinic cell carcinoma. The clinical, radiographic and histologic findings indicated the central origin of the tumor.
  • Naohiko INOUE, Kimie OHYAMA, Keiichi ISHIGURO, Mitsuo AZUMA, Takemasa ...
    1970 年 17 巻 3 号 p. 249-261
    発行日: 1970年
    公開日: 2022/11/12
    ジャーナル オープンアクセス
    An attempt was made to study the process of the separation of the human mid palatal suture by rapid expansion and the subsequent restorative changes. Fixed type orthodontic plates with expansion screws were inserted into eight orthodontic cases with the lateral compression of the maxilla. The amount of the expansion was measured on the occlusal x-ray pictures and the restorative process was observed. The conclusions are summarized as follows: 1. The mid-palatal suture could be separated to some extent in the palatal bone area. 2. The restorative process started by the spicule formation and the ossification were completed two months later. 3. The intra-alveolar changes of the anchor teeth did not exceed the amount of the separation a t the mid-palatal suture. 4. The increase of SNA and the decrease of SNB were dominantly observed, resulting in the significant increase of ANB. 5. No distinct information on the effective age for the application of the rapid expansion could be obtained. 6. The rapid expansion should be an effective method of practical orthodontics to reduce the skeletal deficiency such as the lateral compression of the maxilla as well as the functional interference resulting from the skeletal deficiency.
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