The present study has been performed, in order to elucidate the relationship between inflammation of the nasopharyngeal mucosa and the flora, and agents aggravating inflammation. The results were as follows: 1) There was a parallel relation between the change of the nasopharyngeal flora and clinical symptoms of nasopharyngitis, especially at the time of acute exacerbation of nasopharyngitis. The change of the flora on smears was divided into 6 grades. 2) The cultural characteristics of the flora were divided into 3 types according to the growing mode on the blood agar. The characteristics of the flora had close relations with clinical course of nasopharyngitis. 3) The strain, especially staphylococcus aureus, whose colony frequently showed pure culture on the blood agar was considered as one of the agents aggravating nasopharyngitis. 4) The experiment in rabbits revealed the staphylococcus aureus alone could cause slight nasopharyngitis, but more severe inflammation caused by the bacteria was applied to the nasopharynx with the powder of charcoal. Consequently, it is thought that dust can play an important role in exacerbation of nasopharyngitis.
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