The surface rough ness value of 39 oral squamous cell carcinomas was measured by the Rmax method. The means of the eight measurement values of each carcinoma ranged from 87 µm to 1176 µm. The average value of all 39 lesions was 341 µm. The average value of the lesions of the papillomatous and granulomatous types was larger than that of the leukoplakic and erosive types. The lesions with the size of more than 2 cm in diameter were rougher than those of less than 2 cm. The lesions of the gingiva were rougher than those on the tongue. There was an inclination that the surface of the verrucous carcinoma was rougher than that of the invasive squamous cell carcinoma and that the surface of early carcinoma was smoother than that of the invasive squamous cell carcinoma.
The GFAP-positive cells in the five human anterior pituitaries obtained at autopsy were investigated immunohistochemically and ultramicroscopically. The GFAP-positive cells varied in number from case to case and were identical with the so-called stellate cell. The stellate cells were also involved in the follicular formation. The electron microscopic study showed the various features of these cells. Some had a narrow rim of perikaryon and slender cytoplasmic processes with a moderate number of mitochondria and endoplasmic reticula and others formed an intercellular lumen and follicles with well developed Golgi apparatus, vesicular body and lysozome. The intermediate filaments were rather abundant and the anit-GFAP-positive products were thought to be related with these filaments. The stellate cells were non-granulated so far as examined. The variability of their ultrastructural features were thought to reflect the different physiological state of the pituitary. The present findings suggested the important role of the stellate cells in the function of the endocrine secretary cells. Their origin was also discussed.
Inner ear barotrauma was observed by compressing or decompressing guinea pigs. The barotrauma in compression was greatly influenced by auditory tube function, and, in the animals deprived of this function, we could observe far more severe damage of inner ear hair cells and far more frequent round window rupture than in animals not thus deprived.
Barotrauma in decom pression was brought about in guinea pigs not deprived of auditory tube function with a decompression speed of 0.1 kg/㎠/sec, which is so severe that even a healthy auditory tube could not endure it. It can be said that the middle and inner ear are more apt to be damaged in decompression than in compression.