Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
ISSN-L : 0366-7022
Volume 38 , Issue 2
Showing 1-42 articles out of 42 articles from the selected issue
Highlight Review
  • Jean-Claude G. Bünzli
    2009 Volume 38 Issue 2 Pages 104-109
    Published: February 05, 2009
    Released: December 27, 2008
    Lanthanide luminescent bioprobes (LLBs) are amongst the most sensitive luminescent probes because their excited states are long-lived, which allows time-resolved detection (TRD) of their luminescence, boosting the signal-to-noise ratio and the sensitivity; in addition they are fairly insensitive to photobleaching since lanthanide ions are good quenchers of triplet states. Applications of LLBs to immunoassays, DNA analysis, ligand binding assays, analyte sensing, and cellular imaging are reviewed. Future developments in immunohistochemistry, targeting of specific organelles, lab-on-a-chip technology, and instrumental design are evoked.
    Lanthanide luminescent bioprobes (LLBs) are emerging as essential tools in immunoassays, bioaffinity assays, and cellular microscopy imaging and sensing thanks to their time-resolved capability and multicolor potentiality. Fullsize Image