Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
ISSN-L : 0366-7022
Volume 44 , Issue 11
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  • Suguru Yoshida, Takamitsu Hosoya
    2015 Volume 44 Issue 11 Pages 1450-1460
    Published: November 05, 2015
    Released: November 05, 2015
    [Advance publication] Released: September 12, 2015
    JOURNALS FREE ACCESS
    Recent developments in aryne chemistry are reviewed with a particular focus on synthetic methods. This includes an overview of the precursors of arynes and their activators; the generation of arynes with functional groups and their ensuing reactivities; and the novel transformations achieved via aryne intermediates. These newly developed methods have enabled the synthesis of a variety of previously inaccessible aromatic compounds, allowing the construction of a diversity-enriched chemical library that will further facilitate future drug discoveries.
     
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