Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
ISSN-L : 0366-7022
Volume 49 , Issue 7
Showing 1-30 articles out of 30 articles from the selected issue
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  • Fumi Nagatsugi, Kazumitsu Onizuka
    2020 Volume 49 Issue 7 Pages 771-780
    Published: July 05, 2020
    Released: July 11, 2020
    JOURNALS RESTRICTED ACCESS

    Guanine (G)-rich sequences can form non-canonical four stranded structures known as G-quadruplexes (G4s). The G4 structure has been found in biologically significant regions of the genomic DNA, and many G4 ligands with a high specificity and affinity have been reported. In this review, we focus on the functional G4 ligands, which not only bind to the G4 structure but also have some function, especially with inducing G4 folding, chemical reactions, and alkylation by proximity.

    G-quadruplexes (G4s) are formed in the guaninerich sequences and found in biologically-significant regions of the genomic DNA, including the telomere, located at the end of the eukaryotic chromosome, the promoter regions of oncogenes. In this review, we focus on the functional G4 ligands, which not only bind to the G4 structure but also have some function. Fullsize Image
     
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  • Miki Hasegawa, Hitomi Ohmagari
    2020 Volume 49 Issue 7 Pages 845-854
    Published: July 05, 2020
    Released: July 11, 2020
    JOURNALS RESTRICTED ACCESS

    Luminescent lanthanide (Ln) complexes based on chelate effects will be introduced using a series of hexadentate bipyridine derivatives as their ligand moieties. The molecules form a single helicate molecular structure with a Ln-coordination. Molecular distortion and various derivations induce the intended luminescence and characteristic molecular conformation, which depend on atmosphere or media. It would be a supportive case to design novel units of Ln components for emission.

    Luminescent lanthanide (Ln) complexes based on chelate effect will be introduced by using a series of hexadentate bipyridine derivatives as their ligand moieties. The molecule forms a single helicate molecular structure with a Ln-coordination. Molecular distortion and various derivation induce the intent luminescence and characteristic molecular conformation which depend on atmospheres or media. It would be a supportive case to design novel units of Ln components for emission. Fullsize Image
     
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