Chemistry Letters
Online ISSN : 1348-0715
Print ISSN : 0366-7022
ISSN-L : 0366-7022
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Showing 1-35 articles out of 35 articles from the selected issue
Letter
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  • Sander J. Wezenberg
    2020 Volume 49 Issue 6 Pages 609-615
    Published: June 05, 2020
    Released: June 05, 2020
    JOURNALS RESTRICTED ACCESS

    The ability to control structure and function of metal-organic cages by external stimuli offers many possibilities. For example, preventing product inhibition in catalysis, releasing a drug at a specific site, or altering material properties. This Highlight Review describes the different strategies that have been developed to make light-responsive metal-organic cages able to undergo a structural change in response to a light stimulus and furthermore, major challenges and future perspectives are discussed.

    The ability to control structure and function of metal-organic cages by a light stimulus offers many possibilities. For example, to prevent product inhibition in catalysis, to release a drug at a specific site, or to alter material properties. This Highlight Review describes the different strategies that have been used to make metal-organic cages change their structure in response to light and furthermore, discusses major challenges and future perspectives. Fullsize Image
     
Letter
  • Yusuke Masuda, Katsuhiko Makita, Masahiro Murakami
    2020 Volume 49 Issue 6 Pages 616-618
    Published: June 05, 2020
    Released: June 05, 2020
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    Herein reported is a dehydrative allylation reaction of 2-alkylbenzophenones with allylic alcohols promoted by light and palladium. Photoirradiation of 2-alkylbenzophenones generates nucleophilic species which couple with allylic alcohols. Mechanistically, in-situ generated carboxylic acid is likely to activate allylic alcohols to facilitate the palladium-catalyzed allylation reaction.

  • Hirotomo Nishihara, Kenta Matsuura, Mao Ohwada, Masanori Yamamoto, Yos ...
    2020 Volume 49 Issue 6 Pages 619-623
    Published: June 05, 2020
    Released: June 05, 2020
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    One of the challenging targets in materials synthesis is a direct conversion of molecular based crystalline substances into crystalline ordered carbonaceous frameworks (OCFs). Though we have discovered the first example of the direct conversion with Ni-cyclic porphyrin dimer bridged by diacetylene moieties, such dimer requires a multi-step synthesis procedure with low yield and the resulting OCFs are not highly porous. Herein, we report the direct conversion of Ni-porphyrin monomer with ethynyl groups into OCF with developed microporosity. Upon heat-treatment, Ni-porphyrin monomer is thermally polymerized via ethynyl groups and the resulting polymer is successively converted into OCF at 873 K. Thus, ordered microporous material with conductive carbonaceous framework is obtained. The porphyrin Ni-N4 coordination structure is well retained after the carbonization and the microporous OCF exhibits specific electrocatalysis for CO2 conversion into CO with high selectivity.

Highlight Review
  • Takashi Kitao, Takashi Uemura
    2020 Volume 49 Issue 6 Pages 624-632
    Published: June 05, 2020
    Released: June 05, 2020
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    Recent developments in controlling polymer assemblies using metal–organic frameworks (MOFs) are covered in this highlight review. The characteristic features of MOFs are their highly tailorable and well-defined nanoporous structures that can be utilized for specific polymer nanoconfinement. This methodology allows us to regulate assembly structures of polymers for the fundamental study of polymer properties, as well as construction of functional MOF–polymer nanohybrids.

    Recent developments in controlling polymer assemblies using metal-organic frameworks (MOFs) are covered in this highlight review. The characteristic features of MOFs are their highly tailorable and well-defined nanoporous structures that can be utilized for specific polymer nanoconfinement. This methodology allows us to regulate assembly structures of polymers for the fundamental study of polymer properties, as well as construction of functional MOF-polymer nanohybrids. Fullsize Image
     
Letter
Highlight Review
  • Jun Zhao, Xuzhou Yan
    2020 Volume 49 Issue 6 Pages 659-665
    Published: June 05, 2020
    Released: June 05, 2020
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    Metal–organic polyhedra (MOPs) are discrete porous materials which feature intriguing structures, well-defined cavities, and emergent functions. Among them, the recently developed Rh(II)-based MOPs represent a class of novel assemblies with robust structures, facile processabilities, and versatile functions thanks to the strong Rh–Rh bonds in the paddle-wheel units and the rich chemistries of the unsaturated Rh sites. These distinct characteristics make Rh(II)-based MOPs a prominent platform for the construction of functional materials with integrated discrete porosities. Therefore, in this mini-review, we highlight recent development and advances of Rh(II)-based MOPs as well as their applications from modular entities to supramolecular soft matter.

    Rh(II)-based metal-organic polyhedra (MOPs) represent a novel class of porous metal-coordination complexes with robust structures and unsaturated open metal sites. The rich coordination and covalent chemistries of Rh(II)-based MOPs make them a promising platform for constructing functional materials. Herein, we highlight the development and advances of Rh(II)-based MOPs, as well as their applications from discrete units to supramolecular materials. Fullsize Image
     
Letter
Highlight Review
  • Xiaohan Xu, Haibo Wang, Hongyan Li, Hongzhe Sun
    2020 Volume 49 Issue 6 Pages 697-704
    Published: June 05, 2020
    Released: June 05, 2020
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    Metal/metalloid complexes have been commonly used in medicine as either therapeutic or diagnostic agents. Understanding the molecular mechanisms of action of metallodrugs is crucial for the development of more effective metallodrugs. Metalloproteomics serve as important tools for systematic analysis of metal-bound proteins within a cell or tissue type. Inductively coupled plasma mass spectrometry (ICP-MS), has been widely employed by metalloproteomic approaches. We summarize the latest progress of ICP-MS-based metalloproteomic approaches for the identification of putative protein targets of anticancer and antibacterial metallodrugs with the purpose of exploring their molecular mechanisms of action. The approach can also play a role in systems biology and precision medicine.

    Metal/metalloid complexes have been commonly utlized in medicine for therapeutics and diagnostics. Inductively coupled plasma mass spectrometry (ICP-MS) has been widely applied to unveil the molecular mechanisms of metallodrugs. This review focuses on the most recent applications of ICP-MS based metalloproteomic approaches in characterizing potential protein targets of anticancer and antibacterial metallodrugs and subsequently exploring their molecular mechanisms. Fullsize Image
     
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