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Volume 26 (2011)
- Issue 6 Pages 571-
- Issue 5 Pages 450-
- Issue 4 Pages 366-
- Issue 2 Pages 88-
- Issue 1 Pages 10-
Volume 26, Issue 1
Displaying 1-6 of 6 articles from this issue
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Feature articles “Development of Innovative Diagnosis and Therapeutic Systems based on Nanobiotechnology” Editor : Kazunori Kataoka
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Takahiro Ochiya2011 Volume 26 Issue 1 Pages 10-14
Published: 2011
Released on J-STAGE: April 25, 2011
JOURNAL FREE ACCESSThe existence of circulating miRNAs in the blood of cancer patients has raised the possibility that miRNAs may serve as a novel diagnostic marker. However, the secretory mechanism and biological function, as well as the meaning of the existence of extracellular miRNAs, remain largely unclear.
In this review, we summarize the usefulness of circulating miRNA for cancer diagnosis, prognosis, and therapeutics.View full abstractDownload PDF (464K) -
Akira Matsumoto, Yuji Miyahara2011 Volume 26 Issue 1 Pages 15-19
Published: 2011
Released on J-STAGE: April 25, 2011
JOURNAL FREE ACCESSHerein presented is an overview of the current trend and future perspective of biosensors and the related fields that show rapid advancement as fusion technologies between micro-/nanoelectronics and medicine/biology. Particular attention has been paid to current effort to develop new biosensing principles exploiting a variety of nano-structures and attempts of bio-transistors providing a label-free electrical biosensing platform.View full abstractDownload PDF (847K) -
Yasuhiro Matsumura2011 Volume 26 Issue 1 Pages 20-28
Published: 2011
Released on J-STAGE: April 25, 2011
JOURNAL FREE ACCESSAnticancer agents categorized in DDS based on nanotechnology have been approved. Regarding a pipeline of clinical development of micelle carrier system, total 6 clinical trials are now underway not only in Japan but also in other countries.
In this chapter, clinical status of other formulations of DDS as well as micelle carriers will be described. In addition, cancer stromal targeting therapy recently proposed by us will be discussed.View full abstractDownload PDF (2944K) -
Nobuhiro Nishiyama, Kazunori Kataoka2011 Volume 26 Issue 1 Pages 29-36
Published: 2011
Released on J-STAGE: April 25, 2011
JOURNAL FREE ACCESSThe development of intelligent drug delivery systems(DDS)is essential to the establishment of the advanced medicine including the treatment of intractable diseases, molecular therapy using plasmid DNA and siRNA, regenerative medicine and non-invasive diagnosis and surgical treatment, although several DDS have been approved for clinical use.
In this paper, we review the current state and future prospects of intelligent DDS.View full abstractDownload PDF (562K) -
Hiroshi Iseki2011 Volume 26 Issue 1 Pages 37-45
Published: 2011
Released on J-STAGE: April 25, 2011
JOURNAL FREE ACCESSThe precise navigation surgery using nano device is a symbol of the innovative minimal invasive surgery system that harmonizes the photo-physics technology in the Drug Delivery Systems(DDS)with the image-guided and robot-assisted technology. This nano device can be used as the device that concentrates a photo-sensitizer uniquely in a lesion and it realizes a faster and more precise navigation surgery than the existing PDT(photodynamic therapy)or HIFU(high intensity focused ultrasound)therapy. Finally we propose to materialize the first chemical surgery in the world without the invasive surgical resection for patients.View full abstractDownload PDF (1593K) -
Shinsuke Ohba, Ung-il Chung2011 Volume 26 Issue 1 Pages 46-51
Published: 2011
Released on J-STAGE: April 25, 2011
JOURNAL FREE ACCESSRegenerative medicine aims to regenerate tissues or organs by combining medical findings with engineering techniques. To develop novel tissue-regeneration system, we need to efficiently activate tissue-regeneration signal in vivo by providing carriers with DDS functions.View full abstractDownload PDF (347K)
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