Possibility of bone mineral assessment with dual energy radiographic densitometry method was examined by means of model experiment.
In this method, X-ray penetration ratios through the object at two different energies are measured by using radiographic densitometry and substituted to a first order simultaneous equation whoes constances are mass attenuation coefficients of the two different energy X-rays for bone mineral and soft tissue. The bone mineral content is obtained as a solution of the equation.
The result can be obtained in forms of two dimensional information with high specific resolution, with no necessity of bolus. Therefore, this method is expected to provide, in future, much valuable informations in the region of maxillofacial diagnosis.
X-ray penetration ratios are obtained from comparison between the film density in the image of the object and that of the reference material wedge whoes composition and density are not only precisely defined but also adjusted approximately equal to those of the object, in orde to compensate the lack of reproducibility of X-ray irradiation, the effect of scattered photons and the fluctuation of film speed due to film processing condition.
In the present study, X-ray beams were monochronized by means of tin and tungsten filters in order to reduce the hardening effect of beam quality in the object, so that high accuracy could be obtained in case of using an ordinally diagnostic X-ray generator.
Bone models were made of mixture 3Ca
3 (PO
4)
2·CaCO
3 and methyl-methacrylate so as to adjust the effective atomic number of them to that of bone. These models were wedge shaped because analyses were simple.
Object in the present exiperiment were composed of the bone models mentioned above and an acrylic resin wedge as soft tissue equivalent layer. Amount of calcium salt was measured with accuracy of ± 0.1 g/cm
2 at a point of 3 g/cm
2 total layer.
Causes of error were analyzed and it was suggested that higher accuracy could be possible provided a X-ray generator with uniform field of more monochromatic beam and a homogenous reference wedge were used.
Factors and parameters necessary in case of in-vivo measurment were theoritically discussed and it was pointed out that mass attenuation coefficient for collagen, fat and other tissues, and mass of those tissues exsist in the measurement area should be measured as well as accurate values of mass attenuation coefficient for bone mineral and muscle.
Possibility of triple energy technique was also theoretically discussed and little could be expected for improvement in accuracy.
抄録全体を表示