Three hundred and eleven cases of uterine disorders diagnosed by ventrotomy were retrospectively investigated in rabbits. The most common clinical sign was hemorrhage from the vulva (72.7%), followed by mammary gland abnormality (9.6%), increased abdominal circumference (7.7%), and palpable abdominal mass (6.8%). The results suggest that uterine disorders should be suspected tentatively in seeing female rabbits with these clinical signs. Of all cases, endometrial hyperplasia was most frequently observed in 138 cases (44.4%), and neoplastic lesions were seen in 111 cases (35.7%), which showed that the non neoplasm cases were much more than the neoplastic cases. Hystopathological examination was done in 76 cases, and revealed that uterine adenocasinoma was most popular (31.6%), seen in 24 cases. The perioperative age ranged widely from 10 months to 9 years and 4 months. Three months or less after ventrotomy, 10 rabbits died (3.2%).

View full abstract

A cat was brought to us for the treatment of depression, anorexia, and hypovolemia. We performed an adrenocorticotropic hormone (ACTH) stimulation examination, radiography, ultrasonography, and computed tomography. On the basis of clinical symptoms, a low cortisol level, microcardia, small pulmonary vessels, and small adrenal glands, the condition was diagnosed as hypoadrenocorticism. Imaging findings were useful for obtaining additional information on hypoadrenocorticism. Although hypoadrenocorticism in cats is extremely rare, we would recommend its consideration as a differential diagnosis for cats with nonspecific clinical symptoms and hypovolemia.

View full abstract

We report a rare case of uterine torsion associated with uterine endometrial polyps seen in a non-gravid cat. An 11-year-old Persian cat weighing 2.9 kg with signs of lethargy and anorexia of 3 days' duration showed hypothermia, pallor of the visible mucous membranes, and severe pain on abdominal palpation. Abdominal radiological and ultrasonographic findings revealed what appeared to be an abnormal uterus with two tubular structures containing fluid and a mass inside each structure. In an exploratory laparotomy under general anesthesia, the right uterine horn was found to be dark red and severely twisted. Ovariohysterectomy was performed without correction of the torsion. Hystopathologically, the masses in the uterus were both diagnosed as endometrial polyps. To our knowledge, this is the third case report of uterine torsion in a non-gravid female cat, and also the first reported case of the simultaneous occurrence of uterine torsion and uterine endometrial polyps in a non-gravid cat.

View full abstract

We report two canine cases of a rare disease, large cell anaplasitic lymphoma, which were cytomorphologically classified according to an updated Kiel Classification. Two dogs with severe splenomegaly showed regenerative anemia and thrombocytopenia. Since tumors were found in the spleen on ultrasonograms, splenectomy was performed on both dogs. Cytologic examination revealed that the tumor cells in these cases were quite different from those of common lymphomas, namely, they were larger in size, having wide and highly basophilic cytoplasm with vacuoles, and often showed hemophagositosis. Although histiocytic sarcomas was suspected based on histological and cytological evaluations in both cases, this was found to be false because the tumor cells in case 1 were identified as T cell clones, and in case 2, as B cell clones by clone analysis using polymerase chain reaction.

View full abstract

Hematological deta results were compared retrospectively between 12 ferrets (Mustela putorius furo) diagnosed to be lymphoma and 10 considered clinically to be healthy. In 66.7% (8/12) of all ferrets, anemia was found, and lymphoma was considered to be multicentric lymphoma in many of them. Thrombopenia was noted in 72.7% (8/11) of the ferrets, and many of them had mediastinal lymphoma. Five (41.7%, 5/12) ferrets exhibited leukocytosis, including four (33.3%, 4/12) with lymphocytosis. Thus, ferrets with lymphoma frequently develop anemia and thrombopenia.

View full abstract