This study retrospectively investigated the seroprevalence of the feline leukemia virus (FeLV) antigen and the feline immunodeficiency virus (FIV) antibody, as well as the prevalence of stomatitis and lymphoma in cats admitted to the Yonago Animal Clinical Center (Japan), based on medical records covering the past 12 years. The prevalence of FeLV and FIV, averaged over 12 years, was 7.0% and 16.8% respectively. While lymphoma was present in 0.5%, 14.6%, 1.9%, and 2.7% of the FIV/FeLV-negative, FeLV-positive, FIV-positive, and FIV/FeLV-positive cats, respectively, stomatitis was observed in 16.1%, 25.6%, 27.4%, and 29.7% of the FIV/FeLV-negative, FeLV-positive, FIV-positive, and FIV/FeLV-positive cats, respectively. The mean age of the cats at death was 9.5, 5.9, 10.3, and 6.4 years in the FIV/FeLV-negative, FeLV-positive, FIV-positive, and FIV/FeLV-positive groups, respectively.
With increasing age, dogs exhibit many signs similar to those seen in age-related cognitive dysfunction syndrome (CDS) and dementia in humans. Clinical signs reported by owners likely relate to their specific observations such as house-soiling, changes in sleep–wake cycles, and disorientation. When we reviewed these reported CDS signs in physically healthy dogs aged 6 years and older, signs were noted to increase with age, exceeding 70% at the age of 13 years. Further differences were noted between subgroups. In the 6- to 9-year-old age group, the issues were more common in males than in females. In the 10- to 13-year-old age group, Western type breeds had more issues than Japanese type dogs. And finally, in the 14- to 18-year-old age group, spayed females had more issues than intact females. Degradation of cognitive function was also shown to be related to walks and exercise with the owner. Many owners have noticed behavioral changes affecting their elderly dogs, but few have consulted with a professional. Most of the owners who did not seek care for these changes thought that they were due to aging and would not be a problem.
A 7-year-old Toy Poodle presented with frequent vomiting and vigor of two months’ duration. Medical treatment at another animal hospital improved the patient’s general condition, but the case was referred for further investigation and treatment. An examination revealed gallstones and mucinous cysts in the gallbladder. At the time of surgery, small holes were observed in the gallbladder, and peritonitis and a gallstone in the peritoneal cavity were noted; a cholecystectomy was performed. A 2-year-old Welsh Corgi presented with a month-long history of jaundice and ascites. Ascites, gallstone, and a small perforation in gallbladder were noted on surgery, and a cholecystectomy was performed. After surgery, both dogs showed good recovery.
A 3-year-old cat with a history of persistent erythrocytosis（PCV, 73％）was referred to our hospital. The cat did not show signs of dehydration. Secondary erythrocytosis was excluded by normal percutaneous oxygen saturation (98％) and low serum erythropoietin levels. Bone marrow examination revealed a marked increase in erythroid cells. The cat was diagnosed with polycythemia vera. X-chromosome inactivation pattern（XCIP）analysis of the androgen receptor (AR) gene in bone marrow and peripheral blood samples did not reveal clonality. The presence of JAK2 V617F mutation was not confirmed. Chemotherapy with hydroxycarbamide brought PCV under remission; the medication is still ongoing after over one year.
Six dogs that were diagnosed with hemangiosarcoma were treated by surgery only (3 dogs) and or by administration of doxorubicin after the surgery (3 dogs). The mean survival days for each treatment were 87 days and 189 days, respectively. Thus, the mean survival days for cases that received the latter treatment was 102 days longer than that for cases that received the former treatment.