Epilepsy & Seizure
Online ISSN : 1882-5567
ISSN-L : 1882-5567
2 巻 , 1 号
Review Article
  • Carlos Cepeda, Tatsuya Tanaka, Jean-Marie Stutzmann, Henri Korn
    原稿種別: Review Article
    2009 年 2 巻 1 号 p. 1-16
    発行日: 2009年
    公開日: 2009/02/28
    ジャーナル フリー
    This biographical note pays a small tribute to Robert Naquet, one of the pillars of French epileptology together with Henri Gastaut, his mentor. It can be said that the Marseilles school of epilepsy left an indelible mark in the neurological sciences and that there is no epileptologist, in France and abroad, who was not influenced by the teachings of these two gentlemen. It is practically impossible to separate the scientific achievements of Robert Naquet from his multiple facets as a humanist, artist, and teacher. His warm personality and legendary modesty may serve as an example for future generations of neuroscientists.
Brief Communication
Case Report
  • Kazuhiro Samura, Takato Morioka, Kimiaki Hashiguchi, Yasushi Miyagi, H ...
    原稿種別: Case Report
    2009 年 2 巻 1 号 p. 34-41
    発行日: 2009年
    公開日: 2009/12/06
    ジャーナル フリー
    The coexistence of hippocampal sclerosis (HS) and extrahippocampal lesions such as focal cortical dysplasia (FCD) and cavernoma (CA) in temporal lobe epilepsies (TLE) is termed 'dual pathology'. We report a case of TLE having 'triple pathology' of HS, FCD and CA in the ipsilateral frontal lobe. Using chronic subdural electrode recording, an interictal electrocorticogram (ECoG) demonstrated that the medial temporal lobe lesion and the FCD lesion exhibited independent paroxysmal discharges, while an ictal ECoG demonstrated that the medial temporal lobe was the ictal onset zone. We postulated that the FCD lesion caused repeated seizures, which in turn, caused secondary hippocampal damage and HS, and eventually medically intractable epilepsy. The coexistence of CA was considered incidental. As treatments, the epileptogenic HS was resected through an anterior temporal lobectomy, and the FCD lesion was biopsied, while no surgical intervention was performed for the CA lesion. The patient achieved good seizure control during 12 months after surgery. Chronic subdural electrode recording is important for the assessment of multiple epileptogenic lesions before epilepsy surgery.