We studied what effect the new anabolic agent, stanozolol (17β-hydroxy-17α-methylandrostano-[3, 2-C-] pyrazole) bears on energy metabolism of the aged people.
Subjects were seven aged women of under weight.
They took one tablet (containing 2mg stanozolol) three times a day, after each meal, for 35 days in late autumn of 1963. Afterwards, for 14 days, they did not take stanozolol.
Energy metabolism was measured once a week on basal metabolism by the Douglas bag method.
Results obtained were as follows:
1) Energy metabolism had increased about 10% than before dosage.
2) Oxygen-consumption and carbon dioxide-production had increased most after 21 days, respectively 10%, 7%. After that, both of them had decreased. On stop of dosage, they slowed to increase.
3) Non-protein R. Q. decreased, but after the stop of dosage increased again.
4) Rate of combustion of nutrients which provided energy in the body was different after dosage: carbohydrate reduced about 17%, fat increased approximately 10% and protein increased about 7%.
5) The subjects gained average of 1.4kg in weight for 35 days.
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