Eighteen temporomandibular joint arthrosis patients with TMJ pain were investigated to determine the effectiveness, side effects complication and safety of sodium hyaluronate therapy. 0.5ml of sodium hyaluronate (ARTZ
®) were injected into the painful TMJ of each patient once a week for 4 weeks.
The results were as follows.
1. The vertical interincisal distances significantly increased immediately after injection. But one week later the interincisal distances had decreased nearly up to these before injection. 1 month after injection the mean of interincisal distances again increased significantly.
2. The effectiveness rate (markedly effective and moderately effective), 1 month after injection, was 83% for spontaneous pain, 100% for mouth closing pain, 70% for joint tenderness and 41% for mouth opening pain.
3. Half of the patients who had joint sound before injection found that their click or crepitus had disappeared or lessened 1 month after injection.
4. Complications, including abnormal sensation, swelling sensation, dull sensation and uncomfortable spontaneous pain, mouth opening pain at the site of the joint where the medium was injected or trismus, wera recognized in 56% of cases. All the patients with spontaneous pain complain of some complication.
5. It is concluded that intra-articular injection therapy of hyaluronic acid for the painful temporomandibular joint with TMJ arthrosis is rather safe and useful.
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